NMDA - Moligand™, 100mmol/L in H2O , CAS No.6384-92-5

CAS: 6384-92-5 Cat. No.: N276566 Formule: C₅H₉NO₄ Poids moléculaire: 147.13 Beilstein Registry Number: 1724431

QUALITÉ & PURETÉ Moligand™, 100mmol/L in H2O

Synonyms

(R)-2-(Methylamino)succinic acid hydrochloride|(2R)-2-(methylamino)butanedioic acid|(R)-2-Ethylbutannedioic acid|(R)-2-(Methylamino)succinicacid|METHYL ASPARTIC ACID, D-|Me-D-Asp-OH|N-Me-D-Asp-OH|NMDA (N-Methyl-D-aspartic acid)|N-Methyl aspartic acid|(R)-2-Methylamino-succinic acid|N-Methyl-Daspartate|N-Methyl-D-aspartate|SDCCGSBI-0050753.P003|Lopac-M-3262|N-Methylaspartate|N-methyl-D-aspartic acid|2-Methylamino-succinic acid|NMDA|N-methyl D-aspartate|N-methyl D-aspartic acid|Aspartic acid, N-methyl-|OEM|methyl-d-aspartic acid|Methyl aspartic acid|(NMDA)|D-Aspartic acid, N-methyl-|n-methyl-d-aspartic acid (nmda)|N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Vue d’ensemble

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Spécifications

Synonymes

(R)-2-(Methylamino)succinic acid hydrochloride | (2R)-2-(methylamino)butanedioic acid | (R)-2-Ethylbutannedioic acid | (R)-2-(Methylamino)succinicacid | METHYL ASPARTIC ACID, D- | Me-D-Asp-OH | N-Me-D-Asp-OH | NMDA (N-Methyl-D-aspartic acid) | N-Methyl aspartic acid | (R)-2-Methylamino-succinic acid | N-Methyl-Daspartate | N-Methyl-D-aspa Afficher plus

Spécifications et pureté

Moligand™, 100mmol/L in H2O

Mécanismes biochimiques et physiologiques

Excitotoxic amino acid. Prototypic agonist at the ionotropic NMDA glutamate receptor which is involved in long-term potentiation, ischemia, and epilepsy. Soluble in 1 ml water to give specified mM/ml concentration. Find out more.

Conditions de stockage de stockage

Store at 2-8°C,Desiccated

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Noms et identifiants

Pubchem Sid

528766291

Sourires canoniques

CNC(CC(=O)O)C(=O)O

IUPAC Name

(2R)-2-(methylamino)butanedioic acid

InChIKey

HOKKHZGPKSLGJE-GSVOUGTGSA-N

INCHI

1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1

Isomères SMILES

CN[C@H](CC(=O)O)C(=O)O

RTECS

CI9457000

Poids moléculaire

147.13

Beilstein

1724431

Reaxy-Rn

1724430

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724430&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Aspartic acid and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Aspartic acid and derivatives
• Alternative Parents: D-alpha-amino acids Fatty acids and conjugates Dicarboxylic acids and derivatives Amino acids Dialkylamines Carboxylic acids Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Aspartic acid or derivatives - Alpha-amino acid - D-alpha-amino acid - Dicarboxylic acid or derivatives - Fatty acid - Amino acid - Carboxylic acid - Secondary aliphatic amine - Secondary amine - Amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as aspartic acid and derivatives. These are compounds containing an aspartic acid or a derivative thereof resulting from reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: secondary amino compound - amino dicarboxylic acid - D-alpha-amino acid - D-aspartic acid derivative

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in 1ml of water to give specified mM/ml concentration
• Rotation spécifique [α]: -15° (C=2,H2O)
• Point de fusion (°C): 178 °C
• Poids moléculaire: 147.130 g/mol
• XLogP3: -3.400
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 147.053 Da
• Monoisotopic Mass: 147.053 Da
• Topological Polar Surface Area: 86.600 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 145.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1