NYX-2925 , CAS No.2012536-16-0

CAS: 2012536-16-0 Cat. No.: N649564 Formule: C₁₄H₂₃N₃O₄ Poids moléculaire: 297.35 PubChem CID: 122594417

Synonyms

2012536-16-0 | NYX2925 | NYX-2925 | 2,5-DIAZASPIRO(3.4)OCTANE-2-ACETAMIDE, .ALPHA.-((1R)-1-HYDROXYETHYL)-5-(2-METHYL-1-OXOPROPYL)-1-OXO-, (.ALPHA.S,4R)- | (2S,3R)-3-hydroxy-2-[(4R)-5-(2-methylpropanoyl)-3-oxo-2,5-diazaspiro[3.4]octan-2-yl]butanamide | X06

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be used for research of a variety of NMDA receptor-mediated central nervous system disorders

IC50& Target:NMDA Receptor

Specifications

Synonymes

2012536-16-0 | NYX2925 | NYX-2925 | 2,5-DIAZASPIRO(3.4)OCTANE-2-ACETAMIDE, .ALPHA.-((1R)-1-HYDROXYETHYL)-5-(2-METHYL-1-OXOPROPYL)-1-OXO-, (.ALPHA.S,4R)- | (2S,3R)-3-hydroxy-2-[(4R)-5-(2-methylpropanoyl)-3-oxo-2,5-diazaspiro[3.4]octan-2-yl]butanamide | X06

Mécanismes biochimiques et physiologiques

NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

MODULATOR

Noms et identifiants

• Sourires canoniques: CC(C)C(=O)N1CCCC12CN(C2=O)C(C(C)O)C(=O)N
• IUPAC Name: (2S,3R)-3-hydroxy-2-[(4R)-5-(2-methylpropanoyl)-3-oxo-2,5-diazaspiro[3.4]octan-2-yl]butanamide
• InChIKey: NFXPEHLDVKVVKA-ISTVAULSSA-N
• INCHI: 1S/C14H23N3O4/c1-8(2)12(20)17-6-4-5-14(17)7-16(13(14)21)10(9(3)18)11(15)19/h8-10,18H,4-7H2,1-3H3,(H2,15,19)/t9-,10+,14-/m1/s1
• Isomères SMILES: C[C@H]([C@@H](C(=O)N)N1C[C@@]2(C1=O)CCCN2C(=O)C(C)C)O
• CAS alternatif: 2012536-16-0,1621435-56-0
• PubChem CID: 122594417
• Termes d'entrée MeSH: (2S,3R)-3-hydroxy-2-((R)-5-isobutyryl-1-oxo-2,5-diazaspiro(3.4)octan-2-yl)butanamide;NYX-2925
• Poids moléculaire: 297.35

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: Alpha amino acids and derivatives Pyrrolidinecarboxamides N-acylpyrrolidines N-acyl amines Tertiary carboxylic acid amides Beta lactams Secondary alcohols Azetidines Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Alpha-dipeptide - Alpha-amino acid or derivatives - Pyrrolidine-2-carboxamide - Pyrrolidine carboxylic acid or derivatives - N-acylpyrrolidine - Fatty acyl - N-acyl-amine - Fatty amide - Tertiary carboxylic acid amide - Pyrrolidine - Beta-lactam - Secondary alcohol - Lactam - Carboxamide group - Azetidine - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Alcohol - Aliphatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Foire aux questions

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2012536-16-0, the molecular formula is C14H23N3O4, and the molecular weight is 297.35 g/mol. InChIKey NFXPEHLDVKVVKA-ISTVAULSSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.