Omaciclovir - ≥99% , CAS No.124265-89-0

CAS: 124265-89-0 Cat. No.: O650223 Formule: C₁₀H₁₅N₅O₃ Poids moléculaire: 253.26 PubChem CID: 135433609

GRADE & PURITY ≥99%

Synonyms

OMACICLOVIR [USAN] | (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine | 2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-3H-purin-6-one | AKOS040749068 | Q27275359 | 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(4-hydroxy-2-(hydroxymethyl)butyl)- (R)- | Omaciclo

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

In Vitro

Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys. Omaciclovir shows antiviral activities against different human herpesviruses with EC 50 s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Synonymes

OMACICLOVIR [USAN] | (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine | 2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-3H-purin-6-one | AKOS040749068 | Q27275359 | 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(4-hydroxy-2-(hydroxymethyl)butyl)- (R)- | Omaciclo

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

• Sourires canoniques: C1=NC2=C(N1CC(CCO)CO)N=C(NC2=O)N
• IUPAC Name: 2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-1H-purin-6-one
• InChIKey: SCBFBAWJWLXVHS-ZCFIWIBFSA-N
• INCHI: 1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)3-6(4-17)1-2-16/h5-6,16-17H,1-4H2,(H3,11,13,14,18)/t6-/m1/s1
• Isomères SMILES: C1=NC2=C(N1C[C@@H](CCO)CO)N=C(NC2=O)N
• CAS alternatif: 124265-89-0
• PubChem CID: 135433609
• Poids moléculaire: 253.26

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Imidazopyrimidines
      • Subclass Purines and purine derivatives
        • Level5 Purinones
          • Level6 Hypoxanthines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: Purinones
• Direct Parent: Hypoxanthines
• Alternative Parents: 6-oxopurines Pyrimidones Aminopyrimidines and derivatives N-substituted imidazoles Vinylogous amides Heteroaromatic compounds Azacyclic compounds Primary amines Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-oxopurine - Hypoxanthine - Aminopyrimidine - Pyrimidone - Pyrimidine - N-substituted imidazole - Azole - Heteroaromatic compound - Imidazole - Vinylogous amide - Azacycle - Organooxygen compound - Organonitrogen compound - Primary amine - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Amine - Alcohol - Primary alcohol - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Solubilité: DMSO : 230 mg/mL (908.16 mM; Need ultrasonic)
• Poids moléculaire: 253.260 g/mol
• XLogP3: -1.900
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 253.117 Da
• Monoisotopic Mass: 253.117 Da
• Topological Polar Surface Area: 126.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 348.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 124265-89-0, the molecular formula is C10H15N5O3, and the molecular weight is 253.26 g/mol. InChIKey SCBFBAWJWLXVHS-ZCFIWIBFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.