PCO371 - 10mM in DMSO , CAS No.1613373-33-3

CAS: 1613373-33-3 Cat. No.: P656417 Formule: C₂₉H₃₂F₃N₅O₆S Poids moléculaire: 635.65 PubChem CID: 76283707

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1) , with no effect on PTH type 2 receptor.

In Vitro

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 induces cAMP production with an EC 50 of 2.4 μM in COS-7 cells expressing hPTHR1, and 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC 50 , 17 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:PTHR1

Specifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1) , with no effect on PTH type 2 receptor.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

AGONIST

Noms et identifiants

• Isomères SMILES: CC1=CC(=CC(=C1CCS(=O)(=O)N2CCC3(CC2)C(=O)NC(=N3)C4=CC=C(C=C4)OC(F)(F)F)C)N5C(=O)NC(=O)C5(C)C
• CAS alternatif: 1613373-33-3
• PubChem CID: 76283707
• Termes d'entrée MeSH: 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl) sulfonyl)ethyl)phenyl)-5,5-dimethylimidazolidine-2,4-dione;PCO371
• Poids moléculaire: 635.65