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· · COA & SDS disponible pour chaque produit · Expédition le jour même sur les articles en stock PD 146176 - Moligand™, ≥98%(HPLC) , Inhibitor of 15-LOX-1, CAS No.4079-26-9, Inhibitor of 15-LOX-1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Specifications Synonymes
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Spécifications et pureté
Moligand™, ≥98%(HPLC)
Mécanismes biochimiques et physiologiques
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
15-Lipoxygenase inhibitor
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Mécanisme d'action
Inhibitor of 15-LOX-1
Noms et identifiants Pubchem Sid 504758372 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504758372 Sourires canoniques C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 IUPAC Name 6,11-dihydrothiochromeno[4,3-b]indole InChIKey ZGOOPZVQMLHPFM-UHFFFAOYSA-N INCHI 1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2 Isomères SMILES C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 CAS alternatif 4079-26-9 PubChem CID 297589 Numéro NSC 168807 Termes d'entrée MeSH 6,11-dihydro-5-thia-11-aza-benzo(a)-fluorene;PD 146176;PD-146176 Poids moléculaire 237.32
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Indoles and derivatives Subclass Indoles Intermediate Tree Nodes Not available Direct Parent 3-alkylindoles Alternative Parents 1-benzothiopyrans Alkylarylthioethers Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 3-alkylindole - 1-benzothiopyran - Benzothiopyran - Aryl thioether - Alkylarylthioether - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Thioether - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Solubilité Solvent:DMSO, Max Conc. mg/mL: 23.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 11.87, Max Conc. mM: 50 Poids moléculaire 237.320 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1 Rotatable Bond Count 0 Exact Mass 237.061 Da Monoisotopic Mass 237.061 Da Topological Polar Surface Area 41.100 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 293.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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