≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
PKM2 activator 2 is a pyruvate kinase M2 ( PKM2 ) activitor with an AC 50 value of 66 nM. PKM2 activator 2 may show anti-tumor proliferation effect and relieve the Warburg effect, while PKM2 activation can restore normal glycolytic metabolism in cells
In Vitro
PKM2 leads to increased availability of glycolyctic intermediates for biosynthesis of amino acids, nucleic acids, and lipid building blocks for cellular construction in cancer cells. However, PKM2 shows down-regulated expression and dimeric form in tumors and cancer cell lines. PKM2 activator 2 (compound 28) is a highly potent activator, activates pyruvate kinase with an AC 50 value of 66 nM in the luciferase-coupled assay. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:PKM2 66 nM (EC 50 )
Specifications
Spécifications et pureté
≥99%
Mécanismes biochimiques et physiologiques
PKM2 activator 2 is a pyruvate kinase M2 ( PKM2 ) activitor with an AC 50 value of 66 nM. PKM2 activator 2 may show anti-tumor proliferation effect and relieve the Warburg effect, while PKM2 activation can restore normal glycolytic metabolism in cells
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
ACTIVATOR
Pureté
≥99%
Noms et identifiants
Poids moléculaire
452.49
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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