Poly-L-lysine hydrobromide - Molecular weight: 30000-70000 , CAS No.25988-63-0

CAS: 25988-63-0 Cat. No.: P303255

GRADE & PURITY Molecular weight: 30000-70000

Synonyms

2olb | DTXSID40948891 | L-Lysine, L-lysyl-L-lysyl- | Lys-Lys-Lys | Y7F82M80K8 | SCHEMBL3796535 | (S)-6-Amino-2-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanamido)hexanoic acid | Lysyllysyllysine | lysyl-lysyl-lysine | L-Lysine,L-lysyl-L-lysyl- | (2S)-6-

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

2olb | DTXSID40948891 | L-Lysine, L-lysyl-L-lysyl- | Lys-Lys-Lys | Y7F82M80K8 | SCHEMBL3796535 | (S)-6-Amino-2-((S)-6-amino-2-((S)-2, 6-diaminohexanamido)hexanamido)hexanoic acid | Lysyllysyllysine | lysyl-lysyl-lysine | L-Lysine, L-lysyl-L-lysyl- | (2S)-6-

Specifications & Purity

Molecular weight: 30000-70000

Biochemical and Physiological Mechanisms

Poly-L-lysine is a non-specific attachment factor for cells that can be used to promote cell adhesion to solid substrates by enhancing electrostatic interactions between negatively charged ions of the cell membrane and the culture surface. When it is take

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Pubchem Sid: 504754654
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754654
• Canonical Smiles: C(CCN)CC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)N
• IUPAC Name: (2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoic acid
• InChIKey: WBSCNDJQPKSPII-KKUMJFAQSA-N
• INCHI: 1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1
• Isomeric SMILES: C(CCN)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N
• MeSH Entry Terms: L-Lys-(L-Lys)n-L-Lys•xHBr

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: N-acyl-L-alpha-amino acids Alpha amino acid amides Medium-chain fatty acids Amino fatty acids N-acyl amines Secondary carboxylic acid amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-oligopeptide - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Medium-chain fatty acid - Amino fatty acid - Fatty amide - N-acyl-amine - Fatty acyl - Fatty acid - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Primary aliphatic amine - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organonitrogen compound - Amine - Primary amine - Organooxygen compound - Organic oxygen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Light sensitive
• Molecular Weight: 402.500 g/mol
• XLogP3: -5.600
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 17
• Exact Mass: 402.295 Da
• Monoisotopic Mass: 402.295 Da
• Topological Polar Surface Area: 200.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 463.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Dongchao Qiu, Chuchu Zheng, Youyun Zeng, Lixia Wu, Chen Huang, Ying Ran, Yiqin Ding, Jiayi Shi, Xiaojun Cai, Yihuai Pan.  (2023)  Enzymolysis and photothermal-mediated synergistic antimicrobial nanoplatform with programmed EPS degradation and biofilm penetration capabilities for eradication of biofilm wound infections.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.147217]

2. Shuo Xu, Jun You, Shaorong Yan, Luting Zhu, Xiaochen Wu.  (2023)  Etamsylate loaded oxidized Konjac glucomannan-ε-polylysine injectable hydrogels for rapid hemostasis and wound healing.  Journal of Materials Chemistry B,      [PMID:37830374] [10.1039/D3TB01904G]

3. Hao Wang, Zilei Chen, Chao Zhu, Hongxia Du, Jiangsheng Mao, Hongwei Qin, Yongxin She, Mengmeng Yan.  (2023)  An interference-free SERS-based aptasensor for chlorpyrifos detection.  ANALYTICA CHIMICA ACTA,      [PMID:37268344] [10.1016/j.aca.2023.341398]

4. Ruicheng Xu, Jing Tang, Roja Hadianamrei, Suyu Liu, Songwei Lv, Rongrong You, Fang Pan, Peng Zhang, Nan Wang, Zhiqiang Cai, Xiubo Zhao.  (2023)  Antifungal activity of designed α-helical antimicrobial peptides.  Biomaterials Science,  11  (8): (2845-2859).  [PMID:36857655] [10.1039/D2BM01797K]

5. Wei Zhu, Jing-Yi Tang, Dong Yu, Ai-Guo Shen.  (2022)  Silent Raman imaging of highly effective anti-bacterial activity synchronous with biofilm breakage using poly(4-cyanostyrene)@silver@polylysine nanocomposites.  ANALYST,  148  (3): (628-635).  [PMID:36602005] [10.1039/D2AN01831D]

6. Lina Wang, Duo Yi, Youfu Geng, Tingting Duan, Zhifeng Tong, Shaolan Chen, Zhiyao Ning, Yu Du, Xueming Hong, Xuejin Li.  (2022)  Ultrasensitive deafness gene DNA hybridization detection employing a fiber optic Mach-Zehnder interferometer: Enabled by a black phosphorus nanointerface.  BIOSENSORS & BIOELECTRONICS,      [PMID:36455374] [10.1016/j.bios.2022.114952]

7. Poyu Chen, Chuangwei Zhang, Ping He, Shengyuan Pan, Wenjie Zhong, Yue Wang, Qingyue Xiao, Xinyan Wang, Wenliang Yu, Zhangmin He, Xiang Gao, Jinlin Song.  (2022)  A Biomimetic Smart Nanoplatform as "Inflammation Scavenger" for Regenerative Therapy of Periodontal Tissue.  International Journal of Nanomedicine,      [PMID:36388874] [10.2147/IJN.S384481]

8. Wenjie Zhong, Xinyan Wang, Lanxin Yang, Yue Wang, Qingyue Xiao, Simin Yu, Richard D. Cannon, Yan Bai, Chuangwei Zhang, Duanjing Chen, Ping Ji, Xiang Gao, Jinlin Song.  (2022)  Nanocarrier-Assisted Delivery of Metformin Boosts Remodeling of Diabetic Periodontal Tissue via Cellular Exocytosis-Mediated Regulation of Endoplasmic Reticulum Homeostasis.  ACS Nano,      [PMID:36259964] [10.1021/acsnano.2c08146]

9. Anning Li, Siqi Wang, Zhiqiang Zhang, Na Xu, Guixia Ling, Peng Zhang.  (2022)  Poly-l-lysine derivative-coated black phosphorus as a nanoplatform for photothermal chemotherapy to enhance anti-tumor efficiency.  Journal of Materials Chemistry B,  10  (27): (5191-5202).  [PMID:35726778] [10.1039/D1TB02456F]

10. Yang Hu, Mingxuan Liu, Daquan Zhou, Feng Chen, Qiang Cai, Xiongwei Yan, Jingfeng Li.  (2022)  Gelatine methacrylamide-based multifunctional bilayer hydrogels for accelerating diabetic wound repair.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2022.110687]

11. Xiaomei Dai, Jifang Ma, Ningning Chen, Yuanyuan Cai, Yanping He, Xiangzi Li, Feng Gao.  (2021)  MSNs-Based Nanocomposite for Biofilm Imaging and NIR-Activated Chem/Photothermal/Photodynamic Combination Therapy.  ACS Applied Bio Materials,      [PMID:35014320] [10.1021/acsabm.1c00034]

12. Ya-Min Shen, Meng-Yue Gao, Xu Chen, Ai-Guo Shen, Ji-Ming Hu.  (2021)  Fine synthesis of Prussian-blue analogue coated gold nanoparticles (Au@PBA NPs) for sorting specific cancer cell subtypes.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:33607489] [10.1016/j.saa.2021.119566]

13. Meng-Yue Gao, Qiao Chen, Wei Li, Ai-Guo Shen, Ji-Ming Hu.  (2019)  Combined Surface-Enhanced Raman Scattering Emissions for High-Throughput Optical Labels on Micrometer-Scale Objects.  ANALYTICAL CHEMISTRY,      [PMID:31603655] [10.1021/acs.analchem.9b03357]

14. Chenyue Zhan, Yong Huang, Guifang Lin, Shuailing Huang, Fang Zeng, Shuizhu Wu.  (2019)  A Gold Nanocage/Cluster Hybrid Structure for Whole-Body Multispectral Optoacoustic Tomography Imaging, EGFR Inhibitor Delivery, and Photothermal Therapy.  Small,  15  (33): (1900309).  [PMID:31245925] [10.1002/smll.201900309]

15. Jia-Hong Wu, Fang-Qi Shao, Shi-Yi Han, Song Bai, Jiu-Ju Feng, Zhengquan Li, Ai-Jun Wang.  (2018)  Shape-controlled synthesis of well-dispersed platinum nanocubes supported on graphitic carbon nitride as advanced visible-light-driven catalyst for efficient photoreduction of hexavalent chromium.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:30278328] [10.1016/j.jcis.2018.09.080]

16. Liuyang Xuan, Ming Shi, Shuangshuang Ma, Feng Ye, Xuetao Shi, Ling Yan, Yan Li.  (2018)  Development of Electrospun Composite Fibers in Multiscale Structure and Investigating the Performance on Proliferation and Osteogenic Differentiation of ADSCs.  MACROMOLECULAR MATERIALS AND ENGINEERING,  303  (7): (1800130).  [PMID:] [10.1002/mame.201800130]

17. Xueming Bao, Biaobiao Yan, Yuanyuan Yu, Bo Xu, Li Cui, Man Zhou, Qiang Wang, Ping Wang.  (2024)  A facile cellulose finishing strategy through in-situ growth of sliver-doped manganese dioxide assisted by amine-quinone for improving indoor living quality.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38593901] [10.1016/j.ijbiomac.2024.131448]

18. Jin Bao, Wenping Zeng, Yun Huang, Zhongwei Zhao, Jiajun He, Zhanpeng Du, Fengliang Wang, Huihui Li, Heguo Zeng, Xing Li, Mingshan Wang, Yuanhua Lin, Bingshu Guo, Bo Yu, Haijun Cao.  (2025)  Advancing aqueous zinc-ion battery performance with pullulan through preferential adsorption on zinc anode surfaces and enhanced zinc ion desolvation.  Materials Today Energy,      [PMID:] [10.1016/j.mtener.2024.101790]

19. Yinghao Li, Dongling Xiao, Weixi Yan, Meilin Jiang, Ju Tan, Zhongliang Qin, Jingting Zhou, Yue Sun, Mingcan Yang, Guanyuan Yang, Yawei Gu, Yong Liu, Chuhong Zhu.  (2024)  Bioinspired hierarchical porous tough adhesive to promote sealing of high-pressure bleeding.  Bioactive Materials,      [PMID:39634058] [10.1016/j.bioactmat.2024.11.003]

20. Gong Can, Lu Xiang-Ting, Zhang Shi-Ding, Xiao Kun, Xu Xu.  (2024)  Detection of lard adulteration in 3 kinds of vegetable oils by liquid chromatography–mass spectrometry with porous graphite carbon column.  ANALYTICAL SCIENCES,  40  (7): (1289-1299).  [PMID:38582804] [10.1007/s44211-024-00560-4]

21. You Xiaoxiao, Wang Zhongke, Wang Li, Liu Youbo, Chen Hongmei, Lan Xiaorong, Guo Ling.  (2024)  Graphene oxide/ε-poly-L-lysine self-assembled functionalized coatings improve the biocompatibility and antibacterial properties of titanium implants.  Frontiers in Bioengineering and Biotechnology,      [PMID:38638320] [10.3389/fbioe.2024.1381685]

22. Peng He, Guanghui Gu, Youyin Xu, Gang Wei, Mingjin Xu.  (2025)  Injectable and self-healing dual-network chitosan/hyaluronic acid/polypeptide (CHP) antibacterial hydrogels for wound healing.  POLYMER,      [PMID:] [10.1016/j.polymer.2025.128064]

23. Fu Siyuan, Wang Zhiyu, Huang Peihong, Li Guanjun, Niu Jian, Li Zhiyang, Zu Guangyue, Zhou Pengcheng, Wang Lianhui, Leong David Tai, Ding Xianguang.  (2025)  Programmable production of bioactive extracellular vesicles in vivo to treat myocardial infarction.  Nature Communications,  16  (1): (1-16).  [PMID:40133312] [10.1038/s41467-025-58260-0]

24. Yingjun Yang, Kuankuan Han, Siyuan Huang, Kai Wang, Yuchen Wang, Shukai Ding, Le Zhang, Miao Zhang, Bingshe Xu, Shufang Ma, Yongtao Wang, Shengli Wu, Xinlong Wang.  (2024)  Revelation of Adhesive Proteins Affecting Cellular Contractility through A Reference-free Traction Force Microscopy.  Journal of Materials Chemistry B,      [PMID:38466580] [10.1039/D4TB00065J]

25. Yujie Zhang, Xiaojiang Zhang, Lianxi Lv, Sheng Gao, Xiang Li, Ruochen Wang, Pengqian Wang, Feiyu Shi, Junjun She, Ya Wang.  (2024)  Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease.  CARBOHYDRATE POLYMERS,      [PMID:39647933] [10.1016/j.carbpol.2024.123063]

26. Jiacheng Ding, Xia Gao.  (2025)  Multimodal Lateral Flow Immunoassay Based on Four-in-One Au@Prussian Blue Nanoparticles for Ultrasensitive Higenamine Screening in Urine and Food Samples.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.5c02995]

27. Jing Liu, Mulan Zhu, Na Bai, Nan Huang, Wentai Zhang, Zhilu Yang, Ying Wang.  (2025)  Microfluidic Perfusable Pathological Vasculature for Atherosclerosis Drug Screening.  Research,      [PMID:40979559] [10.34133/research.0902]

28. Shilong Zhang, Shuyang Tan, Yajun Deng, Bo Wu, Yanling Yang, Jiangfan Chang, Xianhui Zhang, Baiyi Chen, Jianhua Wu.  (2025)  pH-Responsive Controlled Release of Antifouling Agents from Polysiloxane Coatings for Marine Propellers.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138373]

29. Lijun Wang, Jing Cao, Zhenni Yu, Haixia Hu, Xiao Yang, Xianggui Chen.  (2025)  A colorimetric/fluorescence dual-mode method using GQDs-regulated Fe3O4@Cu@PLL nanozyme activity for thiamethoxam detection.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115349]

30. Jie Chen, Naiquan Yang, Yi Xu, Yan Ji, Zheng Qian, Jing Sun, Qiuyang Zhang, Qingping Xiong, Changjiang Pan.  (2025)  Construction of an anticoagulant coating mimicking extracellular matrix for better surface blood compatibility and endothelialization of polyurethanes.  POLYMER,      [PMID:] [10.1016/j.polymer.2025.129172]

31. Qianchun Zhang, Shuxin Du, Fengling Tian, Xixi Long, Siqi Xie, Shan Tang, Linchun Bao.  (2022)  Silver Nanoparticle-Functionalised Nitrogen-Doped Carbon Quantum Dots for the Highly Efficient Determination of Uric Acid.  MOLECULES,  27  (14): (4586).  [PMID:35889460] [10.3390/molecules27144586]

32. Lulu Liu, Chenxin Lu, Zhenchao Tao, Zhengbao Zha, Hua Wang, Zhaohua Miao.  (2024)  2D is Better: Engineering Polydopamine into Cationic Nanosheets to Enhance Anti-inflammatory Capability.  Advanced Healthcare Materials,      [PMID:38466315] [10.1002/adhm.202400048]

33. Pinli Lin, Xiaona Tang, Jintao Zhong, Fang Tang, Hanjiao Liu, Lu Peng, Biyu Wan, Mengya Wang, Yuling Ye, Rui Guo, Xusheng Liu, Lili Deng.  (2024)  Antibacterial, ROS scavenging and angiogenesis promoting ε-polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing.  Biofabrication,      [PMID:38408382] [10.1088/1758-5090/ad2d2e]

34. Jie Wu, Jincheng Tang, Lichen Zhang, Wei Wang, Ziang Li, Liang Zhou, Xinzhao Jiang, Yiyang Huang, Qiangqiang Guo, Wenbo Wang, Zhouye Ding, Feng Cai, Kun Xi, Yong Gu, Liang Chen.  (2024)  Biomimetic “Trojan Horse” Fibers Modulate Innate Immunity Cascades for Nerve Regeneration.  ACS Nano,      [PMID:39708371] [10.1021/acsnano.4c12036]

35. Yue Yu, Ziying You, Xin Li, Feng Lou, Ding Xiong, Ling Ye, Zhenming Wang.  (2024)  Injectable Nanocomposite Hydrogels with Strong Antibacterial, Osteoinductive, and ROS-Scavenging Capabilities for Periodontitis Treatment.  ACS Applied Materials & Interfaces,      [PMID:38497587] [10.1021/acsami.3c16577]

36. Xiaochen Xu, Nan Luo, Jing Ru, Hua Zeng, Xiaohao Liu, Shuo Tan, Feng Chen, Bing-Qiang Lu, Xi Chen.  (2025)  Metastable Calcium Phosphate Cluster-Involved Mineralization Process Regulated by a Dual Biomolecule System Toward the Application in Dentinal Tubules Occlusion.  Advanced Healthcare Materials,      [PMID:39981809] [10.1002/adhm.202405074]

37. Yun Liu, Guoqiang Zhang, Jia Chen, Ziying Zhang, Quanxin Wu, Lei Zhang, Shanhui Zhu, Qikai Liang, Zhongtao Wu, Xiliang Luo, Zhen Wang, Weishen Zeng.  (2024)  Photoresponsive protamine ionic complex towards a smart hemostatic biomaterial.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39362436] [10.1016/j.ijbiomac.2024.136212]

38. Zhenjian Li, Hongwei Cheng, Bingzhe Wang, Liming Wang, Jun Wu, Bohan Zhang, Zikang Tang, Songnan Qu.  (2024)  Polylysine-modified near-infrared-emitting carbon dots assemblies: Amplification of tumor accumulation for enhanced tumor photothermal therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:38669991] [10.1016/j.jcis.2024.04.153]

39. Yiming Wang, Chen Wang, Yuan Lu.  (2024)  Spleen Targeting Nucleic Acid Delivery Vector Based on Metal–Organic Frameworks.  ACS Applied Materials & Interfaces,      [PMID:39390629] [10.1021/acsami.4c13519]

40. Xindan Zhang, Wen Guo, Jiangang Zhang, Feng Xiong, Zehao Yao, Jiaqi Lin, Shuyun Hu, Qingsheng Liu, Feng Tian, Nana Zhao, Yonglai Lu, Jiliang Zhai, Yunfeng Lu, Jiajia Xue.  (2025)  Nanofibrous Guidance Conduits with Multiple Gradient Cues for Spinal Cord Repair.  ADVANCED MATERIALS,      [PMID:40296722] [10.1002/adma.202503892]

41. Feng Tao, Chenkai Sun, Yingze Li, Yingying Wang, Peng Ning, Xiaolei Chen, Donglei Yang, Rui Gao, Yuan Li, Chang Xu, Zihan Guo, Haotian Chen, Xing Fan, Li Peng, Cheng Lv, Xinjian Fan, Chang Chen, Yu Cheng.  (2025)  Rotational-bouncing nanomotors with atomic edges for lysosomal mechanoporation.  Matter,      [PMID:] [10.1016/j.matt.2025.102491]

42. Jinli Dou, Juan Li, Jingjing Liu, Jinmeng Shang, Wei Tan, Xia Miao, Jin Zhou, Guifang Guo.  (2024)  A multifunctional nanoplatform for precision-guided therapeutic intervention in bacterial infection.  Journal of Materials Chemistry B,      [PMID:39054879] [10.1039/D4TB01020E]

43. Shuai Jiang, Bo Hao, Xin Song, Yihang Jiang, Junjia Guo, Yuqiong Wang, Qinglong Wang, Xin Wang, Tiantian Xu, Xinyu Wu, Kai Fung Chan, Philip Wai Yan Chiu, Li Zhang.  (2025)  Living Microalgae-Based Magnetic Microrobots for Calcium Overload and Photodynamic Synergetic Cancer Therapy.  Advanced Healthcare Materials,      [PMID:40012437] [10.1002/adhm.202403866]

44. Lingyan Zheng, Zhifang Ning, Yumin Shen, Lei Tang, Sharuna De, Yi Wang, Hong Duan.  (2025)  Multifunctional silver/ε-polylysine/diethyl ferulate composite films with improved anti-UV and antibacterial properties for food packaging.  FOOD RESEARCH INTERNATIONAL,      [PMID:40356161] [10.1016/j.foodres.2025.116367]

45. Kunpeng Liu, Binbin Jiao, Guan Zhang, Zhihua Gan, Shicong Lai, Zhenshan Ding, Qingsong Yu.  (2025)  Self-enhanced ROS-responsive camptothecin prodrug nanoparticles elicit safe and efficient intravesical instillation therapy of bladder cancer.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40449800] [10.1016/j.jconrel.2025.113905]

46. Yanxia Zhang, Nazakaiti Imamaimaiti, Xiaohui Tang, Jua Kim, Tao Jiang, Huiting Fu, Haobo Pan, Yingbo Wang.  (2025)  SiO2-Coated ZnO for Photothermal and Photodynamic Antibacterial Applications in Bone Repair.  ACS Applied Bio Materials,      [PMID:40394494] [10.1021/acsabm.5c00147]

47. Xu Teng, Wang Yaning, Zhao Zechen, Wang Jinsong, Zhao Zhenyuan, Yang Yuemei, Song Xiaomeng, Lai Qingguo.  (2025)  TNFAIP2 promotes NF-κB signaling mediate lymph node metastasis of oral squamous cell carcinoma by protecting IKKβ from ubiquitin proteasome degradation.  Cell Communication and Signaling,  23  (1): (1-17).  [PMID:39948570] [10.1186/s12964-025-02077-3]

48. Hui Ma, Qiuhong Wang, Siyan Li, Huidi Huang, Juan Zhang, Yuanfeng Wang, Wen Wu, Xiaohui Yu, Jiajia Shen.  (2025)  Scalable e-textiles with bio-inspired sea-island electrostatic heterostructures for ion-selective sweat sensing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.170237]

49. Yajuan Yan, Jialian Ding, Wenxuan Fu, Lurong Ding, Wei Hu, Guangzhong Ma, Bin Su.  (2025)  Dual-Pathway Enhanced Single-Molecule Electrochemiluminescence Imaging of T Cell Early Activation Biomarkers.  ANALYTICAL CHEMISTRY,      [PMID:41074783] [10.1021/acs.analchem.5c04037]

50. Longfang Ren, Xin Sun, Jie Miao, Ruilong Li, Huaqing Liu, Sijie Yu, Li Yang, Xiancheng Zhang, Taotao Qiang.  (2025)  A Highly Compatible Polylysine-Based Chrome-Free Tanning Agent: Achieving the Double Benefit of Superior Adsorption to Anionic Materials and Ecological Leather Manufacturing.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.5c07693]

51. Shuai Li, Jianqin Zhang, Hao Wang, Xingyun Zhao, Lin Yang, Lin Chai, Yangyang Liu, Zhangwu Zhao, Bernard Moussian, Abeer El Wakil, Kun Yan Zhu, Zhanghua Zeng, Jianzhen Zhang.  (2025)  Poly-l-lysine functionalized melanin nanocarrier boosts dsRNA delivery and RNAi efficiency in the migratory locust.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.170751]

52. Yanbing Huang, Weifan Niu, Yuanbin He, Xiaojin Zhuang, Zehao Qu, Xin Lan, Chao Zheng, Zhixiong Lin, Fuli Xin, Dongcui Li, Yan Huang, Yu Lin.  (2025)  Flash nano-encapsulation of probiotics: Bolstering environmental resistance and intestinal colonization to prevent necrotizing enterocolitis.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41325905] [10.1016/j.jconrel.2025.114481]

53. Xiao Lin, Haochen Liu, Yan Liu, Qinghua Li, Fan Wu, Ju Zhang, Changxiang Song, Shunyao Jin, Qisheng Liu, Wenlong Li, Qingdong Bao.  (2025)  Commercial orthokeratology lens engineered with multifunctional coatings for intelligently treating bacterial infection and biofouling.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2025.109687]

54. Yahui Du, Wenjiao Wu, Yuexiu Chen, Lihang Zhu, Shuhao Ma, Fengjiang Zhang, Xuejin Li.  (2026)  High-throughput biomimetic cycling of red blood cells: Elucidating the morpho-mechanical determinants of fatigue and clearance.  LAB ON A CHIP,      [PMID:41532666] [10.1039/D5LC01022E]

55. Fengli Chai, Dou Wang, Fenggang Li, Saijie Wang, Yao Chen, Yongzhi Huang, Jiuxin Qu, Shuailong Zhang, Jiangjiang Zhang, Xingyu Jiang.  (2026)  Metal–Organic Framework@Gold Nanoparticles Enables Point-of-Care Diagnostics To Have Comparable Analytical Performance to Chemiluminescent Immunoassays.  ANALYTICAL CHEMISTRY,      [PMID:41507033] [10.1021/acs.analchem.5c04267]

56. J. Busumabu, K. Fatima, H.L. Fan, H.X. Xie, Z.H. Gan, L. Xie, X. Ma, T. Fu.  (2026)  Layer-by-layer coating with addition of Ag3PO4 for antibacterial modification of titanium.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2026.108767]

57. Wenbao Lv, Xueqiang Guo, Lingling Xi, Lei Wang, Han Wang, Qianying Xie, Xiansong Wang, Wenjie Ren.  (2026)  Antimicrobial and Proregenerative Hydrogel Promotes Healing of Infected Diabetic Wounds.  ACS Biomaterials Science & Engineering,      [PMID:41672429] [10.1021/acsbiomaterials.5c02118]

58. Xiaoqi Fang, Yuan Li, Junjie Cui, Zhenye Xu, Zifei Ge, Chengwei Hu, Khurram Abbas, Hong Bi.  (2026)  Light-Responsive Carbon Dots with Photochromism and Excitation-Dependent Room Temperature Phosphorescence.  Advanced Physics Research,      [PMID:] [10.1002/apxr.202500226]