PROTAC EGFR degrader 11 - ≥99% , CAS No.3034244-71-5
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SKU
P1435495
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor ( EGFR ), with DC 50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a K i of 36 nM. PROTAC EGFR degrader 11 degrades EGFR , focal adhesion kinase ( FAK ), and RSK1 , inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC 50 <100 nM.
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| CAS | 3034244-71-5 |
|---|---|
| Spécifications et pureté | ≥99% |
| Conditions de stockage de stockage | Store at 2-8°C |
| Expédié en | Wet ice |
| Product Description | PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor ( EGFR ), with DC 50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a K i of 36 nM. PROTAC EGFR degrader 11 degrades EGFR , focal adhesion kinase ( FAK ), and RSK1 , inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC 50 <100 nM. |
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