≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Conserver à -20°C Ships Glacière + blocs de glace Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
description du produit
Le PTC-209 est un inhibiteur puissant et sélectif de l'IMC-1 dont la CI50 est de 0,5 μM dans la lignée cellulaire HEK293T, et qui entraîne une réduction irréversible des cellules initiatrices de cancer (CIC).
Inhibiteur de Bmi-1 (IC50~ 0,5μM) ; empêche de manière irréversible la croissance des cellules initiatrices du cancer colorectal (CIC). Réduit la croissance tumorale dans les essais de xénogreffes de CIC et réduit le potentiel des cellules cancéreuses col
This compound belongs to the class of organic compounds known as imidazo[1,2-a]pyrimidines. These are aromatic heteropolycyclic compounds containing an imidazole ring fused to and sharing one nitrogen with a pyrimidine ring.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Solvent:DMSO, Max Conc. mg/mL: 49.52, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 9.9, Max Conc. mM: 20
Poids moléculaire
495.200 g/mol
XLogP3
5.500
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
4
Exact Mass
494.919 Da
Monoisotopic Mass
492.921 Da
Topological Polar Surface Area
92.600 Ų
Heavy Atom Count
26
Formal Charge
0
Complexity
480.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
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Foire aux questions
What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 315704-66-6, the molecular formula is C17H13Br2N5OS, and the molecular weight is 495.19 g/mol. InChIKey XVOOCQSWCCRVDY-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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