Puerarin - Moligand™, ≥98% , Activator of TRPV4, CAS No.3681-99-0, Activator of TRPV4

CAS: 3681-99-0 Cat. No.: P111270 Molecular Weight: 416.38 Beilstein Registry Number: 64198 EC Number: 609-296-1
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
AC1NQZ4N | 7-hydroxy-3-(4-hydroxyphenyl)-8-[(3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one | BIDD:ER0101 | BRN 0064198 | SureCN8581666 | Z1494829516 | Z9W8997416 | 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1g
P111270-1g
3
$11.90
5g
P111270-5g
3
$26.90
25g
P111270-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$83.90
100g
P111270-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$276.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 69 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
AC1NQZ4N | 7-hydroxy-3-(4-hydroxyphenyl)-8-[(3R, 4R, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one | BIDD:ER0101 | BRN 0064198 | SureCN8581666 | Z1494829516 | Z9W8997416 | 7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S, 3R, 4R, 5S, 6R)-3, 4, 5-trihydroxy
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Isoflavone component of kudzu. Reduces anxiety symptoms associated with alcohol withdrawal.
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ACTIVATOR
Mechanism of action
Activator of TRPV4
Purity
≥98%
Names and Identifiers
Canonical SmilesC1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
IUPAC Name7-hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
InChIKeyHKEAFJYKMMKDOR-VPRICQMDSA-N
INCHI1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1
Isomeric SMILES C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
WGK Germany 3
RTECS UO5216000
Alternate CAS 3681-99-0
MeSH Entry Terms 7,4'-dihydroxyisoflavone-8beta-glucopyranoside;kakonein;puerarin
Molecular Weight 416.38
Beilstein 64198
Reaxy-Rn 1359060
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1359060&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClassIsoflavonoids
SubclassIsoflavonoid C-glycosides
Intermediate Tree Nodes Not available
Direct ParentIsoflavonoid C-glycosides
Alternative Parents Hydroxyisoflavonoids  Isoflavones  Phenolic glycosides  Hexoses  Chromones  C-glycosyl compounds  1-hydroxy-2-unsubstituted benzenoids  Pyranones and derivatives  Oxanes  Benzene and substituted derivatives  Heteroaromatic compounds  Secondary alcohols  Polyols  Oxacyclic compounds  Dialkyl ethers  Organic oxides  Hydrocarbon derivatives  Primary alcohols  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Isoflavonoid c-glycoside - Isoflavonoid-8-c-glycoside - Hydroxyisoflavonoid - Isoflavone - Phenolic glycoside - Hexose monosaccharide - C-glycosyl compound - Chromone - Glycosyl compound - Benzopyran - 1-benzopyran - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Pyran - Monocyclic benzene moiety - Benzenoid - Oxane - Monosaccharide - Heteroaromatic compound - Secondary alcohol - Organoheterocyclic compound - Oxacycle - Ether - Dialkyl ether - Polyol - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alcohol - Primary alcohol - Organooxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as isoflavonoid c-glycosides. These are c-glycosylated derivatives of isoflavonoids, which are natural products derived from 3-phenylchromen-4-one.
External Descriptors isoflavones - Isoflavonoids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
TRPV4 Tchem Transient receptor potential cation channel subfamily V member 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA12 Tclin Carbonic anhydrase 12 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FABP4 Tchem Fatty acid binding protein adipocyte (764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MGLL Tchem Monoglyceride lipase (1909 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
3T3-L1 (3664 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

20 results found

Lot NumberCertificate TypeDateItem
H2529563Certificate of AnalysisJun 19, 2025 P111270
H2529562Certificate of AnalysisJun 19, 2025 P111270
H2529561Certificate of AnalysisJun 19, 2025 P111270
H2529560Certificate of AnalysisJun 19, 2025 P111270
C2525452Certificate of AnalysisMar 14, 2025 P111270
C2525454Certificate of AnalysisMar 14, 2025 P111270
C2525447Certificate of AnalysisMar 14, 2025 P111270
H2427466Certificate of AnalysisAug 15, 2024 P111270
H2427469Certificate of AnalysisAug 15, 2024 P111270
H2427465Certificate of AnalysisAug 15, 2024 P111270
D2412279Certificate of AnalysisMar 14, 2024 P111270
D2412277Certificate of AnalysisMar 14, 2024 P111270
D2412274Certificate of AnalysisMar 14, 2024 P111270
E2318807Certificate of AnalysisJan 10, 2023 P111270
E2318698Certificate of AnalysisJan 10, 2023 P111270
E2318669Certificate of AnalysisJan 10, 2023 P111270
J2226684Certificate of AnalysisOct 17, 2022 P111270
J2226730Certificate of AnalysisOct 17, 2022 P111270
J2226731Certificate of AnalysisOct 17, 2022 P111270
J2226735Certificate of AnalysisOct 17, 2022 P111270

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Chemical and Physical Properties
SolubilitySoluble in DMSO or DMF. Slightly soluble in water or ethanol
Sensitivityair & heat & Moisture sensitive
Melt Point(°C)187-189°C
Molecular Weight416.400 g/mol
XLogP30.000
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count9
Rotatable Bond Count3
Exact Mass416.111 Da
Monoisotopic Mass416.111 Da
Topological Polar Surface Area157.000 Ų
Heavy Atom Count30
Formal Charge0
Complexity659.000
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Chengyun He, Lu Bai, Daqun Liu, Benguo Liu.  (2023)  Interaction mechanism of okra (Abelmoschus esculentus L.) seed protein and flavonoids: Fluorescent and 3D-QSAR studies.  Food Chemistry-X,      [PMID:38144792] [10.1016/j.fochx.2023.101023]
2. Zheyuan Ren, Yang Yu, Zhongyao Ji, Huitao Li, Xiaoheng Li, Han Lin, Renshan Ge, Qiqi Zhu.  (2023)  Structure-activity relationship and docking analysis of nature flavonoids as inhibitors of human and rat gonadal 3β-hydroxysteroid dehydrogenases for therapeutic purposes.  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY,      [PMID:38143010] [10.1016/j.jsbmb.2023.106450]
3. Shi-Qi Xu, Yi-Nan Du, Zhu-Jun Zhang, Jia-Nan Yan, Jin-Jian Sun, Li-Chao Zhang, Ce Wang, Bin Lai, Hai-Tao Wu.  (2023)  Gel properties and interactions of hydrogels constructed with low acyl gellan gum and puerarin.  CARBOHYDRATE POLYMERS,      [PMID:38142069] [10.1016/j.carbpol.2023.121594]
4. Caiying Zhang, Yuelong Li, Abdus Samad, Hongliang He, Huan Ma, Yang Chen, Tengchuan Jin.  (2023)  Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37924898] [10.1016/j.ijbiomac.2023.127856]
5. Hai-Tao Li, Kun Zhong, Yun-Fei Xia, Jian Song, Xiao-Qing Chen, Wei Zhao, Xu-Hui Zeng, Tian-Xing Chen.  (2023)  Puerarin improves busulfan-induced disruption of spermatogenesis by inhibiting MAPK pathways.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:37516022] [10.1016/j.biopha.2023.115231]
6. Yuan Meng, Zihao Wei, Changhu Xue.  (2023)  Deciphering the interaction mechanism and binding mode between chickpea protein isolate and flavonoids based on experimental studies and molecular simulation.  FOOD CHEMISTRY,      [PMID:37454615] [10.1016/j.foodchem.2023.136848]
7. Fei Wang, Fan Yang, Jiawei Liu, Quan Bai.  (2023)  Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory II. HILIC/RPLC dual-retention mechanism of solutes in hydrophilic interaction chromatography over the entire range of water concentration in mobile phase.  TALANTA,      [PMID:37385194] [10.1016/j.talanta.2023.124858]
8. Ran Tian, Xiue Han, Bo Tian, Guolong Li, Lina Sun, Songfan Tian, Lanxia Qin, Song Wang.  (2023)  Effects of covalent binding of different polyphenols on structure, rheology and functional properties of whey protein isolate.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2023.114968]
9. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu.  (2023)  Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:37290349] [10.1016/j.chroma.2023.464116]
10. Ai-Wen Kang, Chi Sun, Hai-Tao Li, Kun Zhong, Xu-Hui Zeng, Zhi-Feng Gu, Bing-Qian Li, Xiao-Ning Zhang, Jian-Lin Gao, Tian-Xing Chen.  (2023)  Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy.  Food & Function,  14  (4): (2149-2161).  [PMID:36752212] [10.1039/D2FO02800J]
11. Ping Huang, Shi-Xia Du.  (2023)  Puerarin Enhances the Anti-Tumor Effect of Cisplatin on Drug-Resistant A549 Cancer in vivo and in vitro Through Activation of the Wnt Signaling Pathway.  Cancer Management and Research,      [PMID:32801873] [10.2147/CMAR.S253327]
12. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng.  (2023)  Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:36724705] [10.1016/j.plaphy.2023.01.050]
13. Xiaoxiang Gao, Chenbo Yue, Ruocen Tian, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen, Qixiao Zhai.  (2022)  The regulatory effects of specific polyphenols on Akkermansia are dependent on uridine.  FOOD CHEMISTRY,      [PMID:36610089] [10.1016/j.foodchem.2022.135367]
14. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2022)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,      [PMID:36618100] [10.1016/j.crfs.2022.100424]
15. Zafarullah Muhammad, Rabia Ramzan, Ruifen Zhang, Dong Zhao, Nazia Khalid, Mei Deng, Lihong Dong, Mahwash Aziz, Rizwana Batool, Mingwei Zhang.  (2022)  Enhanced Bioaccessibility of Microencapsulated Puerarin Delivered by Pickering Emulsions Stabilized with OSA-Modified Hydrolyzed Pueraria montana Starch: In Vitro Release, Storage Stability, and Physicochemical Properties.  Foods,  11  (22): (3591).  [PMID:36429183] [10.3390/foods11223591]
16. Zeng Wanying, Liu Xiaojing, Wu Yangyang, Cai Yuting, Li Zhennan, Ye Fei, Sun Yuanhong, Li Feng, Xing Huijie, Wang Shuai.  (2022)  Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis.  Frontiers in Pharmacology,      [PMID:36408246] [10.3389/fphar.2022.1053610]
17. Yumin Liu, Ziqi Hu, Jing Wang, Yanjun Liao, Luan Shu.  (2022)  Puerarin alleviates depressive-like behaviors in high-fat diet-induced diabetic mice via modulating hippocampal GLP-1R/BDNF/TrkB signaling.  NUTRITIONAL NEUROSCIENCE,      [PMID:36039913] [10.1080/1028415X.2022.2112439]
18. Jingyi Hu, Yiheng Tong, Zhaofeng Shen, Yanan Li, Cheng Cheng, Ryan Au, Feng Xu, Yajun Liu, Lei Zhu, Hong Shen.  (2022)  Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:36007273] [10.1016/j.biopha.2022.113571]
19. Xiaoling Zeng, Baohui Chen, Luping Wang, Yingxiao Sun, Zhao Jin, Xuanyong Liu, Liping Ouyang, Yun Liao.  (2022)  Chitosan@Puerarin hydrogel for accelerated wound healing in diabetic subjects by miR-29ab1 mediated inflammatory axis suppression.  Bioactive Materials,      [PMID:35600974] [10.1016/j.bioactmat.2022.04.032]
20. Yejun Zhong, Lei Yang, Taotao Dai, Ziyi Zhu, Hongyu Chen, Jianyong Wu, Er Sheng Gong.  (2022)  Flavonoids enhance gel strength of ovalbumin: Properties, structures, and interactions.  FOOD CHEMISTRY,      [PMID:35405558] [10.1016/j.foodchem.2022.132892]
21. Yejun Zhong, Lei Yang, Ziyi Zhu, Hongyu Chen, Chengmei Liu, Taotao Dai, Er Sheng Gong.  (2022)  Protective effect of ovalbumin-flavonoid hydrogel on thrombolytic activity and stability of nattokinase.  FOOD RESEARCH INTERNATIONAL,      [PMID:35651046] [10.1016/j.foodres.2022.111188]
22. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372] [10.1039/D1FO03816H]
23. Yameng Zhu, Mengmeng Zhang, Shujie Wei, Boyao Wang, Jun He, Xilong Qiu.  (2022)  Temperature-responsive P(NIPAM-co-NHMA)-grafted organic-inorganic hybrid hollow mesoporous silica nanoparticles for controlled drug delivery.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2022.103197]
24. Hao Yuan, Wan Li, Chengwu Song, Rongzeng Huang.  (2022)  An injectable supramolecular nanofiber-reinforced chitosan hydrogel with antibacterial and anti-inflammatory properties as potential carriers for drug delivery.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:35149101] [10.1016/j.ijbiomac.2022.02.015]
25. Zhu Tiantian, Zhu Moli, Qiu Yue, Wu Zeqing, Huang Ning, Wan Guangrui, Xu Jian, Song Ping, Wang Shuangxi, Yin Yaling, Li Peng.  (2021)  Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.  Frontiers in Behavioral Neuroscience,      [PMID:34720898] [10.3389/fnbeh.2021.717008]
26. Yang Liu, Xiaoping Zhang, Tengling Wu, Bo Liu, Jianhai Yang, Wenguang Liu.  (2021)  Chinese herb-crosslinked hydrogel bearing rBMSCs-laden polyzwitterion microgels: Self-adaptive manipulation of micromilieu and stemness maintenance for restoring infarcted myocardium.  Nano Today,      [PMID:] [10.1016/j.nantod.2021.101306]
27. Yufen Han, Yarong Lv, Jia Chen, Ming Yao, Ce Wang, Ping Hu, Yong Liu.  (2021)  Electrospun Core–Shell Structure Fibers for Puerarin-Loaded Vascular Grafts.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.1c00633]
28. Liu Jinming, Xu Haiman, Zhang Li, Wang Shuai, Lu Danyi, Chen Min, Wu Baojian.  (2021)  Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα.  Frontiers in Pharmacology,      [PMID:34393786] [10.3389/fphar.2021.707844]
29. Xiangrong Li, Ruonan Xu, Zeqing Cheng, Zhizhi Song, Ziyang Wang, Hanxiao Duan, Xinzhe Wu, Tianjun Ni.  (2021)  Comparative study on the interaction between flavonoids with different core structures and hyaluronidase.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:34175762] [10.1016/j.saa.2021.120079]
30. Lan Mo, Guang-lei Zhao, Xiao-feng Li, Xing-long Xiao, Ning He, Juan-juan Ma, Yi-gang Yu.  (2021)  Evaluation of the digestion and transport profiles and potential immunocompetence of puerarin and its acylated derivatives.  Food & Function,  12  (13): (5949-5958).  [PMID:34031685] [10.1039/D1FO00555C]
31. Zhou Yufeng, Duan Liguang, Huang Yixin, Liu Yaqi, Wang Lijuan, Qiao Xiaoqiang.  (2021)  Ionic Liquid 1-Vinyl-3-dodecylimidazole Bromide Embedded Hybrid Monolithic Column and Its Versatile Post-modification with Amino Acids.  Journal of Analysis and Testing,  (4): (387-395).  [PMID:] [10.1007/s41664-021-00171-2]
32. Yejun Zhong, Jincheng Zhao, Taotao Dai, Jiangping Ye, Jianyong Wu, Tingting Chen, Chengmei Liu.  (2021)  Fabrication of Oil-in-Water Emulsions with Whey Protein Isolate–Puerarin Composites: Environmental Stability and Interfacial Behavior.  Foods,  10  (4): (705).  [PMID:33810424] [10.3390/foods10040705]
33. Yejun Zhong, Jincheng Zhao, Taotao Dai, David Julian McClements, Chengmei Liu.  (2020)  The effect of whey protein-puerarin interactions on the formation and performance of protein hydrogels.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2020.106444]
34. Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen.  (2020)  Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling.  Annals of Hepatology,      [PMID:32980439] [10.1016/j.aohep.2020.07.013]
35. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song.  (2020)  Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:32480277] [10.1016/j.saa.2020.118519]
36. Chunjun Wang, Jihong Yao, Linjie Ju, Xiaohua Wen, Luan Shu.  (2020)  Puerarin ameliorates hyperglycemia in HFD diabetic mice by promoting β-cell neogenesis via GLP-1R signaling activation.  PHYTOMEDICINE,      [PMID:32361558] [10.1016/j.phymed.2020.153222]
37. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang.  (2020)  Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations.  FOOD CHEMISTRY,      [PMID:32330646] [10.1016/j.foodchem.2020.126807]
38. Haifeng Li, Shuang Wang, Fan Cui, Beibei Zhuo, Shuang Wang, Chenrui Zhao, Weilu Liu.  (2020)  Sensitive and selective detection of puerarin based on the hybrid of reduced graphene oxide and molecularly imprinted polymer.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:32145538] [10.1016/j.jpba.2020.113221]
39. Lei Li, Yan Li, Cheng Miao, Rui Liu.  (2020)  Improved Therapeutic Effect of Puerarin-Encapsulated PEG-PLGA Nanoparticle on an In Vitro Cerebral Infarction Model.  ADVANCES IN POLYMER TECHNOLOGY,      [PMID:] [10.1155/2020/7145738]
40. Xue Jintao, Zhou Nanqian, Yang Yuping, Jing Yun, Qiu Yue, Liu Yanhua, Lu Junxiu, Tian Xinqiao, Yin Yaling, Li Peng.  (2020)  Puerarin-loaded ultrasound microbubble contrast agent used as sonodynamic therapy for diabetic cardiomyopathy rats.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:32113166] [10.1016/j.colsurfb.2020.110887]
41. Lili Guo, Huijun Zheng, Cuijie Zhang, Lingbo Qu, Lanlan Yu.  (2019)  A novel molecularly imprinted sensor based on PtCu bimetallic nanoparticle deposited on PSS functionalized graphene with peroxidase-like activity for selective determination of puerarin.  TALANTA,      [PMID:31987162] [10.1016/j.talanta.2019.120621]
42. Duzhen Zhang, Man Li.  (2019)  Puerarin prevents cataract development and progression in diabetic rats through Nrf2/HO‑1 signaling.  Molecular Medicine Reports,  20  (2): (1017-1024).  [PMID:31173182] [10.3892/mmr.2019.10320]
43. Qingqing Hao, Lilin Lu, Xianwen Kan.  (2019)  Probe and analogue: Double roles of thionine for aloe-emodin selective and sensitive ratiometric detection.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2019.04.129]
44. Yunbing Shen, Shengnan Yang, Xueyan Hu, Man Zhang, Xiaoyao Ma, Zhihua Wang, Yuanyuan Hou, Gang Bai.  (2019)  Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells.  Journal of Functional Foods,      [PMID:] [10.1016/j.jff.2019.02.035]
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