≥96%(HPLC) pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.
Store at -20°C,Argon charged Expédition Ice chest + Ice pads. Consultez le COA spécifique au lot pour les spécifications exactes.
SDS, COA, fiche technique et fiche de spécifications disponibles au téléchargement. COA spécifique au lot accessible via la recherche par numéro de lot.
Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.
Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9.
Application：
Raptinal showed complete cytochrome c release within 30 minutes and caspase-3 activation within one hour of exposure (10 μM). Despite its general cytotoxicity in both cancer and non-cancer cell cultures (Cell death induction EC50 = 0.6-3.4 μM in 24 hr), no hematologic toxicity was observed 7 days following single 60 mg/kg i.v. dosing in mice. Studies show that daily i.p. injection (20 mg/kg) is efficacious in suppressing murine B16-F10 melanoma and 4T1 breast cancer expansion in vivo (by ~60% and 50% in 6 days, respectively).
Document complet couvrant les dangers, la manipulation, le stockage et la conformité réglementaire.
<<<<<<< HEAD Télécharger la SDS → ======= Télécharger la SDS → >>>>>>> release248-p3Données qualité spécifiques au lot. Saisissez votre numéro de lot pour récupérer le COA exact.
Rechercher le COA →Résumé de référence rapide des spécifications et applications du produit.
Voir la fiche technique →Attributs de qualité complets et critères d'acceptation pour cette qualité.
Voir la fiche de spécifications →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Fluorenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorenes |
| Alternative Parents | Organic oxides Hydrocarbon derivatives Aldehydes |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Fluorene - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aldehyde - Aromatic homopolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
 H2529565 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529566 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529567 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| J2616092 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| F2415182 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415183 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415204 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415208 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415217 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415241 | Certificate of Analysis | May 08, 2024 | R404974 |
| Solubilité | DMSO: 18.0 mg/mL (46.6 mM), Sonification and heating to 60℃ are recommended. |
|---|---|
| Sensibilité | Air Sensitive,Heat Sensitive |
| Point de fusion (°C) | 219 °C |
| Poids moléculaire | 386.400 g/mol |
| XLogP3 | 4.900 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 386.131 Da |
| Monoisotopic Mass | 386.131 Da |
| Topological Polar Surface Area | 34.100 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 580.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
