QUALITÉ & PURETÉAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥98%(SDS-PAGE)
Accession #
O95750
Protein Tag
N-His
Expression system
E. coli
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
FGF19 is a member of the fibroblast growth factor (FGF) family. FGFs are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. In general, FGFs are expressed during embryonic development and in restricted adult tissues. Human FGF-19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. FGF19-FGFR1 is one of paired transcripts mediating the dialogues between extraembryonic membrane and endometrium. A functional binding ELISA assay was conducted to detect the interaction of Recombinant Human FGF19 Protein (rp145934) and recombinant human FGFR1, the EC50 for this effect is 0.16 μg/mL.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,His-Tag,≥98%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,His Tag pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.
🌡
Stockage & expédition
Store at -80°C,Avoid repeated freezing and thawing Expédition Dry ice packs + Cold packs. Consultez le COA spécifique au lot pour les spécifications exactes.
📋
Documents qualité
SDS, COA, fiche technique et fiche de spécifications disponibles au téléchargement. COA spécifique au lot accessible via la recherche par numéro de lot.
📚
Preuve documentaire
Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.
Vue d’ensemble
Purity
≥ 98% SDS-PAGE.
Function
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
FGF19 is a member of the fibroblast growth factor (FGF) family. FGFs are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. In general, FGFs are expressed during embryonic development and in restricted adult tissues. Human FGF-19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. FGF19-FGFR1 is one of paired transcripts mediating the dialogues between extraembryonic membrane and endometrium. A functional binding ELISA assay was conducted to detect the interaction of Recombinant Human FGF19 Protein (rp145934) and recombinant human FGFR1, the EC50 for this effect is 0.16 μg/mL.
27.7 kDa, under reducing conditions; 27.4 & 54.0 kDa, under non-reducing conditions.
Type de molécule
Protein
Product Line
Produits biologiques
Stockage et expédition
Forme
Lyophilized
Reconstitution
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0mg/mL. Do not vortex.
Conditions de stockage de stockage
Store at -80°C,Avoid repeated freezing and thawing
Expédié en
Dry ice packs + Cold packs
Stabilité et stockage
Avoid repeated freeze/thaw cycles. Store at 2-8℃ for one month. Aliquot and store at -80℃ for 12 month.
Images
Recombinant Human FGF19 Protein (rp145934) - Protein Bioactivity FGF19 is a member of the fibroblast growth factor (FGF) family. FGFs are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. In general, FGFs are expressed during embryonic development and in restricted adult tissues. Human FGF-19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. FGF19-FGFR1 is one of paired transcripts mediating the dialogues between extraembryonic membrane and endometrium. A functional binding ELISA assay was conducted to detect the interaction of Recombinant Human FGF19 Protein (rp145934) and recombinant human FGFR1, the EC₅₀ for this effect is 0.16 μg/mL.
Recombinant Human FGF19 Protein (rp145934) - SDS-PAGE 3 μg/lane of Recombinant Human FGF19 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 27.7 kDa under reducing conditions and 27.4 & 54.0 kDa under non-reducing conditions.
Recombinant Human FGF19 Protein (rp145934) - Binding Activity Immobilized Recombinant Human FGF19 Protein (rp145934) at 2.0 μg/mL can bind Recombinant Mouse Klotho beta Protein (rp184968) with the EC50 of 153.2 ng/mL.
Documentation
📋 Fiche de données de sécurité (FDS)
Document complet couvrant les dangers, la manipulation, le stockage et la conformité réglementaire.
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
Avis
Avis des clients
Besoin d'aide pour choisir la qualité ?
Notre guide de sélection des qualités couvre la pureté, le statut du stabilisant et l'adéquation à l'application pour toutes les variantes de notre catalogue.
Nous utilisons des cookies pour garantir le bon fonctionnement du site et, lorsque cela est autorisé, pour améliorer votre expérience. Vous pouvez gérer vos préférences à tout moment dans les Paramètres. Pour en savoir plus, consultez notre Politique relative aux cookies.
Souhaitez-vous que nous vous envoyions un message lorsque des réductions seront disponibles?
Me rappeler plus tard
Merci ! Veuillez vérifier votre boîte de réception e-mail pour confirmer.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
ZJ23F1101865