Remodelin hydrobromide - 10mM in DMSO , CAS No.1622921-15-6

CAS: 1622921-15-6 Cat. No.: R408429 Formule: C₁₅H₁₅BrN₄S Poids moléculaire: 363.28 PubChem CID: 86280479

GRADE & PURITY 10mM in DMSO

Synonyms

Remodelin HBr | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, hydrobromide (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Remodelin hydrobromide Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.
In vitro

Remodelin, via inhibition of NAT10, mediates nuclear shape rescue of LMNA depleted cells by microtubule reorganization, and improves nuclear shape and fitness of HGPS cells. Remodelin may thus provide opportunities for alleviating dystrophic and premature-ageing diseases.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

Remodelin HBr | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, hydrobromide (1:1)

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Propriétés du produit

• ALogP: 4.031
• Nombre de HBD: 1
• Liaison rotative: 3

Noms et identifiants

• Isomères SMILES: C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1.Br
• PubChem CID: 86280479
• Poids moléculaire: 363.28

Propriétés chimiques et physiques

• DMSO (mg/mL) Solubilité maximale: 72
• DMSO (mM) Solubilité maximale: 198.1942303
• Eau (mg/mL) Solubilité maximale: ＜1

Foire aux questions

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1622921-15-6, the molecular formula is C15H15BrN4S, and the molecular weight is 363.28 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.