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· · COA & SDS disponible pour chaque produit · Expédition le jour même sur les articles en stock Resiquimod - Moligand™, 10mM in DMSO , Toll-like receptor 7 agonist, CAS No.144875-48-9, Toll-like receptor 7 agonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
R848 | AS-30885 | DTXSID20908251 | AKOS016003509 | MLS006010212 | NCGC00370784-05 | R 848 | UNII-V3DMU7PVXF | E 3B Red | EX-A1879 | GTPL5051 | Q27289271 | HY-145079 | BDBM50241029 | MFCD00937759 | Resiquimod (R-848) | RESIQUIMOD [MI] | ResiquimodR848 | RX
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonymes
R848 | AS-30885 | DTXSID20908251 | AKOS016003509 | MLS006010212 | NCGC00370784-05 | R 848 | UNII-V3DMU7PVXF | E 3B Red | EX-A1879 | GTPL5051 | Q27289271 | HY-145079 | BDBM50241029 | MFCD00937759 | Resiquimod (R-848) | RESIQUIMOD [MI] | ResiquimodR848 | RX
Spécifications et pureté
Moligand™, 10mM in DMSO
Mécanismes biochimiques et physiologiques
Toll-like receptor 7 (TLR7) agonist. Induces upregulation of IL-6, IL-12, IFN-γand iNOS expression in mouse bone marrow-derived macrophages (BMMs). Inhibits RANKL-induced osteoclast differentiation in mouse BMMs and human peripheral blood monocytes. Also
Conditions de stockage de stockage
Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Mécanisme d'action
Toll-like receptor 7 agonist
Propriétés du produit Noms et identifiants Pubchem Sid 528776397 Sourires canoniques CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N IUPAC Name 1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol InChIKey BXNMTOQRYBFHNZ-UHFFFAOYSA-N INCHI 1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19) Isomères SMILES CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N WGK Allemagne 3 RTECS NJ5911320 PubChem CID 159603 Poids moléculaire 314.38
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Quinolines and derivatives Subclass Imidazoquinolines Intermediate Tree Nodes Not available Direct Parent Imidazoquinolines Alternative Parents Aminoquinolines and derivatives Imidazo-[4,5-c]pyridines Aminopyridines and derivatives N-substituted imidazoles Imidolactams Benzenoids Tertiary alcohols Heteroaromatic compounds Dialkyl ethers Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Imidazoquinoline - Aminoquinoline - Imidazopyridine - Imidazo-[4,5-c]pyridine - Aminopyridine - Imidolactam - Benzenoid - Pyridine - N-substituted imidazole - Azole - Imidazole - Heteroaromatic compound - Tertiary alcohol - Dialkyl ether - Ether - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Amine - Alcohol - Organopnictogen compound - Organic oxygen compound - Primary amine - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as imidazoquinolines. These are aromatic heterocyclic compounds containing an imidazole ring fused to a quinoline ring system. In some configurations, the imidazole ring shares a nitrogen atom with the quinoline moiety. External Descriptors imidazoquinoline Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Solubilité Solvent:DMSO, Max Conc. mg/mL: 31.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 15.72, Max Conc. mM: 50 Sensibilité Moisture sensitive；Heat sensitive Point de fusion (°C) 193℃ Poids moléculaire 314.400 g/mol XLogP3 1.300 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 5 Exact Mass 314.174 Da Monoisotopic Mass 314.174 Da Topological Polar Surface Area 86.200 Ų Heavy Atom Count 23 Formal Charge 0 Complexity 406.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
FAQ et articles Citations of This Product Références 1. Zhen Wang, Zhangyi Miao, Zhiting Cao, Jianye Ren, Xiaohong Zhu, Yu Sheng, Hao Cheng, Huaqing Zhang, Jianping Zhou, Yang Ding. (2025) Mild Hyperthermia-Assisted Coaxial Electrospun Nanofiber Patches for Epicutaneous Allergen-Specific Immunotherapy. ADVANCED FUNCTIONAL MATERIALS, [PMID: [10.1002/adfm.202509955 ]
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