Determine the necessary mass, volume, or concentration for preparing a solution.
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0 μM).
Appearance:Solid
IC50& Target:IC50: 11.1 μM (RAD51-mediated D-loop formation)
In Vitro:RI(dl)-2 stabilizes nucleoprotein filaments in a nonfunctional state, which are incapable of D-loop activity and simultaneously shielded from related (e.g., RAD52-mediated) pathways that promote single-strand annealing (SSA). RI(dl)-2 does not modula
Biological Activity:RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0 μM).
| Canonical Smiles | CCNC1=CC=C(C2=NC3=C(N4C2=CC=C4)C=CC=C3)C=C1.OC(C(F)(F)F)=O.[1.3] |
|---|---|
| Molecular Weight | 435.59 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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