RIPK1-IN-4 - Moligand™,10mM in DMSO , CAS No.1481641-08-0

CAS: 1481641-08-0 Cat. No.: R655286 Formule: C₂₃H₂₃N₅O₂ Poids moléculaire: 401.46 PubChem CID: 71816195

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase

IC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)

Specifications

Spécifications et pureté

Moligand™,10mM in DMSO

Mécanismes biochimiques et physiologiques

RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Noms et identifiants

Isomères SMILES

CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC=CC4=C3C=CN=C4N

PubChem CID

71816195

Poids moléculaire

401.46

Cibles associées (humaines)

RIPK1 Tchem Receptor-interacting serine/threonine-protein kinase 1 (3 Activities)

Discover Target: RIPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)