RSVA 405 - ≥98%(HPLC) , CAS No.140405-36-3

CAS: 140405-36-3 Cat. No.: R286690 Molecular Weight: 312.37 EC Number: 167-403-2 PubChem CID: 135400298
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
R286690-10mg
10
$323.90
5mg
R286690-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$210.90
50mg
R286690-50mg
3
$753.90
100mg
R286690-100mg
3
$1,137.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

product description:

RSVA 405, an analog of resveratol, is an activator of AMPK with EC50 of 1 μM and an inhibitor of acetyl-CoA carboxylase (ACC).

Specifications

Synonyms
2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
AMP-activated protein kinase (AMPK) activator (EC50= 1μM); activates AMPK indirectly through a CaMKKβ-dependent mechanism. Also inhibits LPS-induced STAT3 phosphorylation (IC50= 0.5μM). Induces autophagy and promotes Aβdegradationin vitro. Also inhibits a
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ACTIVATOR
Purity
≥98%(HPLC)
Names and Identifiers
Pubchem Sid504773254
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504773254
Canonical SmilesCCN(CC)C1=CC(=C(C=C1)C=NNC(=O)C2=CC=NC=C2)O
IUPAC NameN-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide
InChIKeyGWQPCBPAOAFXSJ-XDHOZWIPSA-N
INCHI1S/C17H20N4O2/c1-3-21(4-2)15-6-5-14(16(22)11-15)12-19-20-17(23)13-7-9-18-10-8-13/h5-12,22H,3-4H2,1-2H3,(H,20,23)/b19-12+
Isomeric SMILES CCN(CC)C1=CC(=C(C=C1)/C=N/NC(=O)C2=CC=NC=C2)O
PubChem CID 135400298
Molecular Weight 312.37

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPyridines and derivatives
SubclassPyridinecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentPyridinecarboxylic acids and derivatives
Alternative Parents Phenylalkylamines  Aniline and substituted anilines  Phenoxides  Heteroaromatic compounds  Carboxylic acids and derivatives  Azacyclic compounds  Organooxygen compounds  Organic zwitterions  Organic salts  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Pyridine carboxylic acid or derivatives - Aniline or substituted anilines - Phenylalkylamine - Phenoxide - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Carboxylic acid derivative - Azacycle - Hydrocarbon derivative - Organic zwitterion - Organic oxide - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organic salt - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyridinecarboxylic acids and derivatives. These are compounds containing a pyridine ring bearing a carboxylic acid group or a derivative thereof.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(non-human)
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
B23211010Certificate of AnalysisDec 10, 2025 R286690
B23211011Certificate of AnalysisDec 10, 2025 R286690
B23211094Certificate of AnalysisDec 10, 2025 R286690
B2321993Certificate of AnalysisDec 10, 2025 R286690
H2204087Certificate of AnalysisMay 12, 2025 R286690
H2204088Certificate of AnalysisMay 12, 2025 R286690
H2204089Certificate of AnalysisMay 12, 2025 R286690
B23111010Certificate of AnalysisJan 03, 2022 R286690
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 15.62, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 1.56, Max Conc. mM: 5;<15.62mg/ml in DMSO;insoluble in ethanol
Molecular Weight312.370 g/mol
XLogP32.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass312.159 Da
Monoisotopic Mass312.159 Da
Topological Polar Surface Area77.800 Ų
Heavy Atom Count23
Formal Charge0
Complexity392.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

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