(S)-(+)-Ibuprofen - Moligand™, 10 mM in DMSO , CAS No.51146-56-6

CAS: 51146-56-6 Cat. No.: S1499229 Formule: (CH₃)₂CHCH₂C₆H₄CH(CH₃)CO₂H Poids moléculaire: 206.28 Beilstein Registry Number: 3590022 Numéro CE: 610-620-9

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

(S)-(+)-Ibuprofen ((S)-Ibuprofen), a S(+)-enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC 50 s of 2.1 μM and 1.6 μM, respectively. (S)-(+)-Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects .

Specifications

Spécifications et pureté

Moligand™, 10 mM in DMSO

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Propriétés du produit

• ALogP: 3.5

Noms et identifiants

• Isomères SMILES: C[C@@H](C1=CC=C(C=C1)CC(C)C)C(=O)O
• WGK Allemagne: 3
• Poids moléculaire: 206.28
• Beilstein: 3590022
• Reaxy-Rn: 2049713
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2049713&ln=

Propriétés chimiques et physiques

• Rotation spécifique [α]: 59°
• Point d'éclair (°F): >235.4 °F
• Point d'éclair (°C): >113 °C
• Point de fusion (°C): 49-53°C

Références

1. Lumei Dai, Shifang Wen, Yaling Chen, Xinchun Li, Bing Zhao, Xinyu You, Rongqiang Li, Bin Zhang.  (2025)  Self-assembled dual-target ibuprofen-irinotecan conjugate for colorectal cancer therapy.  BIOORGANIC & MEDICINAL CHEMISTRY,      [PMID:40850193] [10.1016/j.bmc.2025.118367]

2. Dan Xiao, Ying Jin, Mengyu Zhang, Xiangjie Di, Lisha Fu, Changke Jiang, Zhuoli Lai, Yating Ge, Shanmian Ji, Yuming Zhang, Li Zheng, Zhenlei Wang, Fang Gong.  (2023)  Chiral pharmacokinetics of ibuprofen enantiomers in Chinese preterm neonates with patent ductus arteriosus using a validated UHPLC-MS/MS method.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:37454407] [10.1016/j.jchromb.2023.123765]

3. Zhenfei Wang, Bin Liang, Yanan Hou, Si Li, Li Xie, Liang Peng, Peng Zhang, Aijie Wang, Hui Yun, Xiangkai Li.  (2022)  Weak electrostimulation enhanced the microbial transformation of ibuprofen and naproxen.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:35489501] [10.1016/j.scitotenv.2022.155522]

4. Zefang Wang, Yan Peng, Chengjun Shi, Liping Wang, Xiaohong Chen, Wanwan Wu, Xu Wu, Yiming Zhu, Jingchen Zhang, Guiliang Cheng, Songlin Zhuang.  (2021)  Qualitative and quantitative recognition of chiral drugs based on terahertz spectroscopy.  ANALYST,  146  (12): (3888-3898).  [PMID:34042921] [10.1039/D1AN00500F]

5. Qian Han, Cun Wang, Pingkun Liu, Gui Zhang, Li Song, Yingzi Fu.  (2021)  Achieving synergistically enhanced dual-mode electrochemiluminescent and electrochemical drug sensors via a multi-effect porphyrin-based metal-organic framework.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.129388]

6. Fang Wang, Bin Wang, Han Qu, Wenxing Zhao, Lei Duan, Yizhe Zhang, Yitong Zhou, Gang Yu.  (2020)  The influence of nanoplastics on the toxic effects, bioaccumulation, biodegradation and enantioselectivity of ibuprofen in freshwater algae Chlorella pyrenoidosa.  ENVIRONMENTAL POLLUTION,      [PMID:32315820] [10.1016/j.envpol.2020.114593]

7. Mingxia Liu, Lixia Chen, Tingting Tian, Zhiguo Zhang, Xiangjun Li.  (2019)  Identification and Quantitation of Enantiomers by Capillary Electrophoresis and Circular Dichroism Independent of Single Enantiomer Standard.  ANALYTICAL CHEMISTRY,      [PMID:31591882] [10.1021/acs.analchem.9b03276]

8. Tuanjia Li, Wangchuan Xiao, Shizhao Ren, Rongrong Xue, Fenghua Chen.  (2024)  Metastable Racemic Ibuprofen Supercooled Liquid.  Crystals,  14  (12): (1037).  [PMID:] [10.3390/cryst14121037]

9. Duo Xu, Yantian Ji, Bowen Du, Bo He, Hongyang Chen, Huimin Sun, Xianqiang Yin.  (2024)  The synergistic effect of typical chiral organic acids and solution chemistry conditions on the transport of 2-arylpropionic acid chiral derivatives in porous media.  ENVIRONMENTAL POLLUTION,      [PMID:38703979] [10.1016/j.envpol.2024.124059]

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 51146-56-6, the molecular formula is C13H18O2, and the molecular weight is 206.28 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.