Saralasin TFA - ≥98% , CAS No.S658680

CAS: S658680 Cat. No.: S658680 Formule: C₄₄H₆₆F₃N₁₃O₁₂ Poids moléculaire: 1026.07

QUALITÉ & PURETÉ ≥98%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a K i value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Sa

Appearance:Solid

IC50& Target:Ki: 0.32 nM (Angiotensin II receptor)

In Vitro:Saralasin TFA (1 nM, 48 or 72 h) inhibits cell growth in 3T3 and SV3T3 cells. Saralasin TFA (5 μM, 2h) restores I to, fast (Fast-Inactivating Transient Outward K+ Current in Mouse Ventricle) and I K, slow (Slow-Inactivating Transient Outward K+ Curre

In Vivo:Saralasin TFA (intravenous injection, 5-50 μg/kg, a single dose) ameliorates the oxidative stress and tissue injury in cerulein-induced pancreatitis. Saralasin TFA (subcutaneous injection, 10 and 30mg/kg, a single dose) increases serum renin activit

Biological Activity:Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a K i value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Sa

Spécifications

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Desiccated,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

Poids moléculaire

1026.07

Propriétés chimiques et physiques

• Solubilité: H2O : 100 mg/mL (97.46 mM; Need ultrasonic) DMSO : 50 mg/mL (48.73 mM; Need ultrasonic)

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is S658680, the molecular formula is C44H66F3N13O12, and the molecular weight is 1026.07 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.