SHP2-IN-9 - ≥98% , CAS No.S658641

CAS: S658641 Cat. No.: S658641 Formule: C₂₀H₂₀FN₃O₂S Poids moléculaire: 385.46

QUALITÉ & PURETÉ ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

SHP2-IN-9 is a specific SHP2 inhibitor ( IC 50 =1.174 μM) with enhanced blood–brain barrier penetration. SHP2-IN-9 shows 85-fold more selective for SHP2 than SHP1. SHP2-IN-9 inhibits SHP2-mediated cell signal transduction and cancer cell proliferation, an

Appearance:Solid

In Vitro:SHP2-IN-9 (compound 2) could effectively inhibit SHP2-mediated cell signaling pathways in cancer (cervix cancer, human pancreatic cancer, large cell lung cancer and mouse glioma cell) by inhibiting the phosphorylation of Paxillin, affecting the regulation

Biological Activity:SHP2-IN-9 is a specific SHP2 inhibitor ( IC 50 =1.174 μM) with enhanced blood–brain barrier penetration. SHP2-IN-9 shows 85-fold more selective for SHP2 than SHP1. SHP2-IN-9 inhibits SHP2-mediated cell signal transduction and cancer cell proliferation, an

Spécifications

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

Sourires canoniques

O=C(NCC1=CC=C(C=C1)F)CN2C=NC3=C(C4=C(S3)CCCCC4)C2=O

Poids moléculaire

385.46