Sinomenine Hydrochloride - analytical standard, ≥97% , CAS No.6080-33-7

CAS: 6080-33-7 Cat. No.: S101688 Formule: C₁₉H₂₃NO₄·HCl Poids moléculaire: 365.85 Numéro CE: 683-119-6 PubChem CID: 5464452

GRADE & PURITY Analytical standard, ≥97%

Synonyms

Sabianine A hydrochloride | UNII-ZL8HD4RP5B | Q27254812 | S0926 | NSC76021 | 9alpha,13alpha,14alpha -7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one hydrochloride | 7,8-Didehydro-3,7-dimethoxy-4-hydroxy-17-methyl-9-alpha,13-alpha,14-alpha-m

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonymes

Sabianine A hydrochloride | UNII-ZL8HD4RP5B | Q27254812 | S0926 | NSC76021 | 9alpha,13alpha,14alpha -7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one hydrochloride | 7,8-Didehydro-3,7-dimethoxy-4-hydroxy-17-methyl-9-alpha,13-alpha,14-alpha-m

Spécifications et pureté

analytical standard, ≥97%

Mécanismes biochimiques et physiologiques

Natural anti-inflammatory morphinan analog, able to weakly bind to the μ-opioid receptor. Potently releases histamine following mast cell degranulation. Inhibits oligomeric amyloid-β-induced increases in ROS, NO and other inflammatory molecules.

Conditions de stockage de stockage

Store at 2-8°C

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Étalon d'analyse

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥97%

Noms et identifiants

Pubchem Sid

528776406

Sourires canoniques

CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC.Cl

IUPAC Name

(1R,9S,10S)-3-hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one;hydrochloride

InChIKey

YMEVIMJAUHZFMW-VUIDNZEBSA-N

INCHI

1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1

Isomères SMILES

CN1CC[C@@]23CC(=O)C(=C[C@@H]2[C@@H]1CC4=C3C(=C(C=C4)OC)O)OC.Cl

WGK Allemagne

3

RTECS

QD2170000

CAS alternatif

115-53-7

PubChem CID

5464452

Poids moléculaire

365.85

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Alkaloids and derivatives
    • Classe Morphinans

• Kingdom: Organic compounds
• Superclass: Alkaloids and derivatives
• Classe: Morphinans
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Morphinans
• Alternative Parents: Phenanthrenes and derivatives Benzazocines Isoquinolones and derivatives Tetralins Anisoles 1-hydroxy-4-unsubstituted benzenoids Cyclohexenones Aralkylamines Alkyl aryl ethers Piperidines Quaternary ammonium salts Trialkylamines Azacyclic compounds Organic zwitterions Organic oxides Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Morphinan - Phenanthrene - Benzazocine - Isoquinolone - Tetralin - Anisole - Phenol ether - Cyclohexenone - 1-hydroxy-4-unsubstituted benzenoid - Aralkylamine - Phenol - Alkyl aryl ether - Piperidine - Benzenoid - Quaternary ammonium salt - Cyclic ketone - Tertiary aliphatic amine - Ketone - Tertiary amine - Azacycle - Ether - Organoheterocyclic compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic salt - Organic nitrogen compound - Organic zwitterion - Carbonyl group - Organic chloride salt - Amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as morphinans. These are polycyclic compounds with a four-ring skeleton with three condensed six-member rings forming a partially hydrogenated phenanthrene moiety, one of which is aromatic while the two others are alicyclic.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Point de fusion (°C): 231℃
• Poids moléculaire: 365.800 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 365.139 Da
• Monoisotopic Mass: 365.139 Da
• Topological Polar Surface Area: 59.000 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 562.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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