SNT-207707 - 10mM in DMSO , CAS No.1064662-40-3

CAS: 1064662-40-3 Cat. No.: S656484 Formule: C₃₂H₄₄ClN₅O Poids moléculaire: 550.18 PubChem CID: 131843715

QUALITÉ & PURETÉ 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC 50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.

In Vitro

SNT-207707 binds to the MC-4 receptor with an affinity of 8 nM and shows a more than 200-fold selectivity vs. MC-3 and MC-5. SNT207858 is a 22 nM MC-4 antagonist with a 170-fold selectivity vs. MC-3 and a 40-fold selectivity versus MC-5. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Single subcutaneous injection of 20 mg/kg of SNT-207707 distinctly increases food intake of the mice. Once daily oral administration of both compounds SNT207858 and SNT-207707 starting the day after tumor implantation significantly reduces the tumor induced weight loss . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 8 nM (binding MC-4), 5 nM (function MC-4)

Spécifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC 50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.

Conditions de stockage de stockage

Desiccated,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

PubChem CID

131843715

Poids moléculaire

550.18

Foire aux questions

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1064662-40-3, the molecular formula is C32H44ClN5O, and the molecular weight is 550.18 g/mol.

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.