Solifenacin succinate - 10mM in Water , Muscarinic acetylcholine receptor M2 antagonist, CAS No.242478-38-2, Muscarinic acetylcholine receptor M2 antagonist

CAS: 242478-38-2 Cat. No.: S408550 Formule: C23H26N2O·C4H6O4 Poids moléculaire: 480.55 Numéro CE: 620-505-5 PubChem CID: 216457
DISPONIBLE À COMMANDE
GRADE & PURITY 10mM in Water
Synonyms
YM905 | Butanedioic acid, compd. with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Allemagne (EU)
USA*
Price
Qty
1ml
S408550-1ml
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1 En stock

104,04€

150,90€
Enregistrer 46,86 € (31.05%)
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Why this grade

10mM in Water for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Information

Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.
In vitro

Solifenacin succinate is a new muscarinic receptor antagonist developed for the treatment of overactive bladder. The affinity constants (pKi) of solifenacin for recombinant human muscarinic M1, M2 and M3 receptors are 7.6, 6.9 and 8.0, respectively. Hence, the muscarinic M3 receptor subtype selectivity of solifenacin over the muscarinic M2 receptor subtype is readily apparent, but is only marginal over the muscarinic M1 receptor subtype. In the same study, solifenacin and oxybutynin inhibit muscarinic M3 receptor-mediated intracellular Ca2+ mobilization in bladder smooth muscle cells isolated from guinea pigs and in submandibular gland cells isolated from mice.

In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonymes
YM905 | Butanedioic acid, compd. with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
Spécifications et pureté
10mM in Water
Mécanismes biochimiques et physiologiques
Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.
Conditions de stockage de stockage
Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
ANTAGONIST
Mécanisme d'action
Muscarinic acetylcholine receptor M2 antagonist
Noms et identifiants
Isomères SMILES
C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5.C(CC(=O)O)C(=O)O
PubChem CID
216457
Poids moléculaire
480.55

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Cibles associées (humaines)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriétés chimiques et physiques
SolubilitéSolubility (25°C) In vitro DMSO: 59 mg/mL (197.5 mM); Water: 59 mg/mL (197.5 mM); Ethanol: Insoluble;
Point de fusion (°C)147 °C
Calculateurs de solution
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