SRX3177 is a triple inhibitor of CDK4/6 , PI3K , and BRD4 , with IC 50 s of 33 nM (BRD4 BD1), 89 nM (BRD4 BD2), 79 nM ( PI3Kα ), 83 nM ( PI3Kδ ), 3.18 μM ( PI3Kγ ), <2.5 nM ( CDK4 ), 3.3 nM ( CDK6 ), respectively. SRX3177 exerts broad cytotoxic activity against cancer cells, but acts friendly with normal epithelial cells.

Specifications

Specifications & Purity

≥99%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

Molecular Weight	584.69

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SRX3177 - ≥99% , CAS No.2241237-51-2

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Literature proof

Overview