STING agonist-22 , CAS No.2408723-12-4

CAS: 2408723-12-4 Cat. No.: S650797 Formule: C₄₀H₄₈N₁₄O₆ Poids moléculaire: 820.90

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research.

In Vitro

STING agonist-22 (CF501) leads to rapid and robust activation of innate immune responses in THP-1 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

STING agonist-22 (CF501) robustly, but transiently, activates innate immunity with acceptable safety profile in mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Balb/c mice (female, six weeks old) Dosage: 20, 75 μg Administration: Intramuscular injection Result: Although innate immunity was activated only transiently by CF501, it should be sufficient to stimulate the required humoral and cellular immune responses. The half-life of CF501 was 0.5 h and there was no detectable CF501 in the plasma after 2 h of the injection.

Form:Solid

Specifications

Mécanismes biochimiques et physiologiques

STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

• Sourires canoniques: NC(C1=CC2=C(N=C1)N(C/C=C/CN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=C3C(OCCCN6CCOCC6)=CC(C(N)=O)=C5)C(NC(C7=CC(C)=NN7CC)=O)=N2)=O
• Poids moléculaire: 820.90

Foire aux questions

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2408723-12-4, the molecular formula is C40H48N14O6, and the molecular weight is 820.90 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.