Streptolysin O - lyophilized powder,Protein ~3 % by Lowry,25,000-50,000 U/vial, from Streptococcus pyogenes , CAS No.98072-47-0

CAS: 98072-47-0 Cat. No.: S477654 Numéro CE: 308-500-3 PubChem CID: 135280160
DISPONIBLE À COMMANDE
GRADE & PURITY lyophilized powder,Protein ~3 % by Lowry,25,000-50,000 U/vial, from Streptococcus pyogenes
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
★
Size
Allemagne (EU)
USA*
Price
Qty
25KU
S477654-25KU
—
2 En stock
173,46€
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Why this grade

lyophilized powder,Protein ~3 % by Lowry,25,000-50,000 U/vial, from Streptococcus pyogenes for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Description

Used to create holes (reversible pores) in cholesterol-enriched plasma membranes of eukaryotic cells allowing selective permeabilization with molecules such as proteins (up to 100 kDa) and siRNAs.Streptolysin O is a toxin secreted byStreptococcus pyogenesand is a prototype member of poreforming bacterial cytolysins. It is used permeabilize cell membranes to permit cellular uptake of large or charged molecules. It is used to study macromolecule delivery. It is a potential anticancer agent and is used to study suicide cancer gene therapy.Permeabilizes membranes to permit cellular uptake of large or charged molecules.


Preparation instructions



Form

Lyophilized powder containing Tris buffer salts, sodium azide, PMSF, and EDTA.


Principle


Specifications

Spécifications et pureté
lyophilized powder,Protein ~3 % by Lowry,25,000-50,000 U/vial, from Streptococcus pyogenes
Mécanismes biochimiques et physiologiques
Streptolysin O possesses a single polypeptide chain with a molecular weight of f62 kDa. Streptolysin O binds to membrane cholesterol and oligomerizes to create a ring structure that consists of 45 to 50 units. The ring structure inserts into the membran
Conditions de stockage de stockage
Store at 2-8°C,Desiccated
Expédié en
Wet ice
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Noms et identifiants
Pubchem Sid528776203
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/528776203
WGK Allemagne 3
PubChem CID 135280160

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateArticle
H2618471Certificate of AnalysisAug 11, 2026 S477654
H2621096Certificate of AnalysisAug 11, 2026 S477654
H2316666Certificate of AnalysisMay 20, 2026 S477654
C2631453Certificate of AnalysisMar 20, 2026 S477654
F2520561Certificate of AnalysisMay 07, 2025 S477654
L2419506Certificate of AnalysisDec 12, 2024 S477654
Propriétés chimiques et physiques
Solubilité H2O: soluble 1mg/mL
SensibilitéMoisture Sensitive
Calculateurs de solution
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