SU5204 - ≥98%, EZ tautomeric mixture , CAS No.186611-11-0

CAS: 186611-11-0 Cat. No.: S412303 Formule: C₁₇H₁₅NO₂ Poids moléculaire: 265.31 PubChem CID: 6509031

QUALITÉ & PURETÉ ≥98%, EZ tautomeric mixture

Synonyms

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Information

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM forFLK-1 (VEGFR-2)andHER2, respectively.

Targets

VEGFR-2 (Cell-free assay); HER2 (Cell-free assay) 4 μM; 51.5 μM

Spécifications

Synonymes

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

Spécifications et pureté

≥98%, EZ tautomeric mixture

Mécanismes biochimiques et physiologiques

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Propriétés du produit

ALogP

3.063

Nombre de HBD

1

Liaison rotative

3

Noms et identifiants

Pubchem Sid

504764270

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504764270

Sourires canoniques

CCOC1=CC=CC=C1C=C2C3=CC=CC=C3NC2=O

IUPAC Name

(3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one

InChIKey

MEZFKCPUSMBMAY-KAMYIIQDSA-N

INCHI

1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-

PubChem CID

6509031

Poids moléculaire

265.31

Propriétés chimiques et physiques

• Solubilité: Solubility (25°C) In vitro DMSO: 53 mg/mL (199.76 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO (mg/mL) Solubilité maximale: 53
• DMSO (mM) Solubilité maximale: 199.766311107761
• Eau (mg/mL) Solubilité maximale: ＜1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 186611-11-0, the molecular formula is C17H15NO2, and the molecular weight is 265.31 g/mol. InChIKey MEZFKCPUSMBMAY-KAMYIIQDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.