Sulconazole Nitrate - ≥95% , CAS No.61318-91-0

CAS: 61318-91-0 Cat. No.: S129489 Formule: C₁₈H₁₅Cl₃N₂S·HNO₃ Poids moléculaire: 460.76 Numéro CE: 624-696-6 PubChem CID: 65495

QUALITÉ & PURETÉ ≥95%

Synonyms

HMS1570B21 | Sulcosyn | Sulconazole nitrate (JAN/USP) | SULCONAZOLE NITRATE (MART.) | SULCONAZOLE NITRATE [JAN] | SULCONAZOLE NITRATE [VANDF] | RS-44872-00-1O-3 | SW196439-3 | 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Vue d’ensemble

Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity.
An antifungal agent which prevents fungal growth by inhibiting sterol synthesis.

Spécifications

Synonymes

HMS1570B21 | Sulcosyn | Sulconazole nitrate (JAN/USP) | SULCONAZOLE NITRATE (MART.) | SULCONAZOLE NITRATE [JAN] | SULCONAZOLE NITRATE [VANDF] | RS-44872-00-1O-3 | SW196439-3 | 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric

Spécifications et pureté

≥95%

Mécanismes biochimiques et physiologiques

Sulconazole nitrate salt is an antifungal agent which prevents fungal growth by inhibiting sterol synthesis.Antifungal imidazole derivative. Possesses a broad spectrum of activity against dermatophytes, yeasts and some Gram-positive bacteria. Heme oxygena

Conditions de stockage de stockage

Store at 2-8°C,Protected from light

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥95%

Noms et identifiants

Pubchem Sid

488183686

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183686

Sourires canoniques

C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

IUPAC Name

1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid

InChIKey

CRKGMGQUHDNAPB-UHFFFAOYSA-N

INCHI

1S/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

Isomères SMILES

C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

WGK Allemagne

3

RTECS

NI4475000

PubChem CID

65495

Poids moléculaire

460.76

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Halobenzenes
        • Level5 Chlorobenzenes
          • Level6 Dichlorobenzenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Halobenzenes
• Intermediate Tree Nodes: Chlorobenzenes
• Direct Parent: Dichlorobenzenes
• Alternative Parents: N-substituted imidazoles Aryl chlorides Organic nitrates Heteroaromatic compounds Organic nitro compounds Organic nitric acids Sulfenyl compounds Dialkylthioethers Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 1,3-dichlorobenzene - Aryl chloride - Aryl halide - N-substituted imidazole - Azole - Imidazole - Heteroaromatic compound - Organic nitrate - Organic nitro compound - Organic nitric acid - Organic nitric acid or derivatives - Azacycle - Organoheterocyclic compound - Dialkylthioether - Organic 1,3-dipolar compound - Thioether - Sulfenyl compound - Allyl-type 1,3-dipolar organic compound - Organic oxygen compound - Organic nitrogen compound - Organohalogen compound - Organopnictogen compound - Organochloride - Organonitrogen compound - Organosulfur compound - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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HSP90AA1 Tchem Heat shock protein HSP 90-alpha (1 Activities)

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HSP90AA1 Tchem Heat shock protein HSP 90-alpha (4115 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO 92 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
• Sensibilité: Light & Moisture sensitive
• Point de fusion (°C): 152 °C
• Poids moléculaire: 460.800 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 458.998 Da
• Monoisotopic Mass: 458.998 Da
• Topological Polar Surface Area: 109.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 404.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3