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| Description | Platelet-derived growth factor receptor alpha |
|---|
Gene and Protein Information
| Gene ID | 5156 |
|---|---|
| Uniprot Accession IDs | P16234 B2RE69 E9PBH0 Q6P4H5 Q96KZ7 Q9UD28 PDGF-R-alpha |
| Ensembl ID | ENSP00000257290 |
| Symbole | PDGFR2 RHEPDGFRA CD140A PDGFR2 PDGFR-2 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
| Sequence | MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL Afficher plus |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nom | Numéro d'identification fiscale | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 461318 | PDGFRA | platelet derived growth factor receptor alpha | 9598 | OMA, EggNOG | |
| Macaque | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 9544 | Inparanoid, EggNOG | ||
| Mouse | 18595 | Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 10090 | MGI:97530 | Inparanoid, OMA, EggNOG |
| Rat | 25267 | Pdgfra | platelet derived growth factor receptor alpha | 10116 | RGD:3284 | Inparanoid, OMA, EggNOG |
| Dog | 442860 | PDGFRA | platelet derived growth factor receptor alpha | 9615 | VGNC:44372 | Inparanoid, OMA, EggNOG |
| Horse | 100059815 | PDGFRA | platelet derived growth factor receptor alpha | 9796 | VGNC:21261 | Inparanoid, OMA, EggNOG |
| Cow | 282301 | PDGFRA | platelet derived growth factor receptor alpha | 9913 | VGNC:32692 | Inparanoid, OMA, EggNOG |
| Opossum | 100013088 | PDGFRA | platelet derived growth factor receptor alpha | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100084432 | PDGFRA | platelet derived growth factor receptor alpha | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 395509 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 9031 | CGNC:10416 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100565834 | pdgfra | platelet derived growth factor receptor alpha | 28377 | Inparanoid, OMA | |
| Xenopus | 100124862 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | 8364 | XB-GENE-6072920 | Inparanoid, OMA, EggNOG |
| Zebrafish | 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | 7955 | ZDB-GENE-990415-208 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / PDGFR family / Platelet-derived growth factor receptor alpha
protein / Kinase / Protein kinase / TK group / PDGFR family / Platelet-derived growth factor receptor alpha
Associated Recombinant Proteins
| Nom | Specification and purity | Expression system | Protein label | Disponibilité | Voir les détails |
|---|
Associated Antibodies
| Nom | Spécifications | Species reactivity | Application | Disponibilité | Voir les détails |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nom | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
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