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| Description | DNA polymerase alpha catalytic subunit |
|---|
Gene and Protein Information
| Gene ID | 5422 |
|---|---|
| Uniprot Accession IDs | P09884 Q86UQ7 |
| Ensembl ID | ENSP00000368349 |
| Symbole | POLA NSX POLA p180 |
| Family | Belongs to the DNA polymerase type-B family. |
| Sequence | MAPVHGDDSLSDSGSFVSSRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAVTKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTETPQITPPPVMILKKKRSIGASPNPFSVHTATAVPSGKIASPVSRKEPPLTPVPLKRAEFAGDDVQVESTEEEQESGAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEPAEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKKNVKVEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRSNMPKLGGRSGFGERNATCGRMICDVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQFSRTGPLCPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFAGCAVKS Afficher plus |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nom | Numéro d'identification fiscale | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 100611187 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9598 | VGNC:8330 | OMA, EggNOG |
| Macaque | 699763 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 18968 | Pola1 | polymerase (DNA directed), alpha 1 | 10090 | MGI:99660 | Inparanoid, OMA, EggNOG |
| Rat | 85241 | Pola1 | DNA polymerase alpha 1, catalytic subunit | 10116 | RGD:621816 | Inparanoid, OMA, EggNOG |
| Dog | 480869 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9615 | VGNC:44771 | Inparanoid, OMA, EggNOG |
| Horse | 100052225 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9796 | VGNC:21649 | Inparanoid, OMA, EggNOG |
| Cow | 534848 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9913 | VGNC:33110 | Inparanoid, OMA, EggNOG |
| Opossum | 100011328 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 418593 | POLA1 | DNA polymerase alpha 1, catalytic subunit | 9031 | CGNC:12201 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100553905 | pola1 | DNA polymerase alpha 1, catalytic subunit | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100379926 | pola1 | polymerase (DNA directed), alpha 1, catalytic subunit | 8364 | XB-GENE-1000548 | Inparanoid, OMA, EggNOG |
| Zebrafish | 317740 | pola1 | polymerase (DNA directed), alpha 1 | 7955 | ZDB-GENE-030114-9 | Inparanoid, OMA, EggNOG |
| C. elegans | 176544 | pola-1 | DNA polymerase | 6239 | OMA, EggNOG | |
| Fruitfly | 42553 | DNApol-alpha180 | DNA polymerase alpha 180kD | 7227 | FBgn0259113 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 855621 | POL1 | DNA-directed DNA polymerase alpha catalytic subunit POL1 | 4932 | S000005046 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Nom | Specification and purity | Expression system | Protein label | Disponibilité | Voir les détails |
|---|
Associated Antibodies
| Nom | Specifications | Species reactivity | Application | Disponibilité | Voir les détails |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nom | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
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