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DPYD

DescriptionDihydropyrimidine dehydrogenase [NADP(+)]

Gene and Protein Information

Gene ID1806
Uniprot Accession IDs Q12882 A2RRQ2 A2RRQ3 A8K5A2 A8MWG9 B1AN21 E9PFN1 Q16694 Q16761 Q32NB0 Q96HL6 Q96TH1 DHPDHase
Ensembl ID ENSP00000359211
Symbole DHP DPD DHPDHASE
FamilyBelongs to the dihydropyrimidine dehydrogenase family.
Sequence
MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEKMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDVVNFEIELMKDLGVKIICGKSLSVNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFNRWGLPEVDPETMQTSEAWVFAGGDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYLKSIEELQDWDGQSPATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIRLKEQNVAFSPLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCNDSGYQAIQFDPETHLPTITDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPLSVNPVC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomNuméro d'identification fiscale Other Gene IDSources
Chimp457047DPYDdihydropyrimidine dehydrogenase9598VGNC:10605OMA, EggNOG
Macaque715672DPYDdihydropyrimidine dehydrogenase9544Inparanoid, OMA, EggNOG
Mouse99586Dpyddihydropyrimidine dehydrogenase10090MGI:2139667Inparanoid, OMA, EggNOG
Dog479935DPYDdihydropyrimidine dehydrogenase9615VGNC:40081Inparanoid, OMA, EggNOG
Horse100057177DPYDdihydropyrimidine dehydrogenase9796VGNC:17302Inparanoid, OMA, EggNOG
Cow281124DPYDdihydropyrimidine dehydrogenase9913VGNC:28193Inparanoid, OMA, EggNOG
Pig397109DPYDdihydropyrimidine dehydrogenase9823Inparanoid, OMA, EggNOG
Opossum100032923DPYDdihydropyrimidine dehydrogenase13616Inparanoid, OMA, EggNOG
Chicken429083DPYDdihydropyrimidine dehydrogenase9031CGNC:4104Inparanoid, OMA
Zebrafish405829dpydbdihydropyrimidine dehydrogenase b7955ZDB-GENE-040426-2459OMA, EggNOG
C. elegans180818dpyd-1Dihydropyrimidine dehydrogenase [NADP(+)]6239Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    dehydrogenase    /    Dihydropyrimidine dehydrogenase [NADP(+)]
protein    /    oxidoreductase    /    reductase    /    Dihydropyrimidine dehydrogenase [NADP(+)]
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Dehydrogenase    /    Dihydropyrimidine dehydrogenase [NADP(+)]

Associated Recombinant Proteins

NomSpecification and purityExpression systemProtein labelDisponibilitéVoir les détails

Associated Antibodies

NomSpecificationsSpecies reactivityApplicationDisponibilitéVoir les détails

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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