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| Description | Tyrosine-protein kinase ABL1 |
|---|
Gene and Protein Information
| Gene ID | 25 |
|---|---|
| Uniprot Accession IDs | P00519 A3KFJ3 Q13869 Q13870 Q16133 Q17R61 Q45F09 |
| Ensembl ID | ENSP00000361423 |
| Symbole | ABL JTK7 ABL JTK7 p150 c-ABL v-abl CHDSKM c-ABL1 bcr/abl |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. |
| Sequence | MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR Afficher plus |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nom | Numéro d'identification fiscale | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 107976801 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9598 | VGNC:4596 | OMA, EggNOG |
| Macaque | 722449 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 11350 | Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 10090 | MGI:87859 | Inparanoid, OMA, EggNOG |
| Rat | 311860 | Abl1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 10116 | RGD:1584969 | Inparanoid, OMA, EggNOG |
| Dog | 491292 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9615 | Inparanoid, OMA, EggNOG | |
| Horse | 100069715 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9796 | VGNC:49495 | Inparanoid, OMA, EggNOG |
| Cow | 540876 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9913 | VGNC:50224 | Inparanoid, OMA, EggNOG |
| Pig | 100524544 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76] | 13616 | Inparanoid, EggNOG | ||
| Platypus | 100075676 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 417181 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 9031 | CGNC:2837 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100557530 | abl1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 28377 | Inparanoid, OMA | |
| Xenopus | abl1 | ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:Xenbase;Acc:XB-GENE-6054675] | 8364 | OMA, EggNOG | ||
| Zebrafish | 100000720 | abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 7955 | ZDB-GENE-100812-9 | Inparanoid, OMA |
| Fruitfly | 45821 | Abl | Abl tyrosine kinase | 7227 | FBgn0000017 | Inparanoid, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / ABL family / Tyrosine-protein kinase abl1
protein / Kinase / Protein kinase / TK group / ABL family / Tyrosine-protein kinase abl1
Associated Recombinant Proteins
| Nom | Specification and purity | Expression system | Protein label | Disponibilité | Voir les détails |
|---|
Associated Antibodies
| Nom | Spécifications | Species reactivity | Application | Disponibilité | Voir les détails |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nom | Direct Associated Targets | Disease Type | Mondoid |
|---|
Bibliography
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