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ERBB4

DescriptionReceptor tyrosine-protein kinase erbB-4

Gene and Protein Information

Gene ID2066
Uniprot Accession IDs Q15303 B7ZLD7 B7ZLE2 B7ZLE3 Q2M1W1 Q59EW4
Ensembl ID ENSP00000342235
Symbole HER4 HER4 ALS19 p180erbB4
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Sequence
MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
Afficher plus
Homologous gene and protein info.
SpeciesGene IDGene SymbolNomNuméro d'identification fiscale Other Gene IDSources
Chimp459919ERBB4erb-b2 receptor tyrosine kinase 49598VGNC:372OMA, EggNOG
Macaque693341ERBB4erb-b2 receptor tyrosine kinase 49544OMA, EggNOG
Mouse13869Erbb4erb-b2 receptor tyrosine kinase 410090MGI:104771Inparanoid, OMA, EggNOG
Rat59323Erbb4erb-b2 receptor tyrosine kinase 410116RGD:620486Inparanoid, OMA, EggNOG
Dog488508ERBB4erb-b2 receptor tyrosine kinase 49615VGNC:40437Inparanoid, OMA, EggNOG
Horse100050182ERBB4erb-b2 receptor tyrosine kinase 49796VGNC:17651Inparanoid, OMA, EggNOG
Opossum100014865ERBB4erb-b2 receptor tyrosine kinase 413616Inparanoid, OMA, EggNOG
Platypus100077353ERBB4erb-b2 receptor tyrosine kinase 49258Inparanoid, OMA, EggNOG
Chicken395671ERBB4erb-b2 receptor tyrosine kinase 49031CGNC:49428Inparanoid, OMA
Anole lizard100558986erbb4erb-b2 receptor tyrosine kinase 428377Inparanoid, OMA
Xenopus100493234erbb4erb-b2 receptor tyrosine kinase 48364XB-GENE-877077Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    EGFR family    /    Receptor tyrosine-protein kinase erbb-4

Associated Recombinant Proteins

NomSpecification and purityExpression systemProtein labelDisponibilitéVoir les détails

Associated Antibodies

NomSpecificationsSpecies reactivityApplicationDisponibilitéVoir les détails

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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