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SLC6A4

DescriptionSodium-dependent serotonin transporter

Gene and Protein Information

Gene ID6532
Uniprot Accession IDs P31645 Q5EE02 SERT
Ensembl ID ENSP00000261707
Symbole HTT SERT HTT 5HTT OCD1 SERT 5-HTT SERT1 hSERT 5-HTTLPR
FamilyBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
Sequence
METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV
Afficher plus
Homologous gene and protein info.
SpeciesGene IDGene SymbolNomNuméro d'identification fiscale Other Gene IDSources
Chimp468201SLC6A4solute carrier family 6 member 49598VGNC:9626OMA, EggNOG
Macaque574140SLC6A4solute carrier family 6 member 49544Inparanoid, OMA, EggNOG
Mouse15567Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 410090MGI:96285Inparanoid, OMA, EggNOG
Rat25553Slc6a4solute carrier family 6 member 410116RGD:3714Inparanoid, OMA, EggNOG
Dog491184SLC6A4solute carrier family 6 member 49615VGNC:46465Inparanoid, OMA, EggNOG
Horse100033848SLC6A4solute carrier family 6 member 49796VGNC:23261OMA, EggNOG
Cow282365SLC6A4solute carrier family 6 member 49913VGNC:49971Inparanoid, OMA, EggNOG
Pig100517307SLC6A4solute carrier family 6 member 49823OMA, EggNOG
Opossum100015330SLC6A4solute carrier family 6 member 413616Inparanoid, OMA, EggNOG
Chicken404747SLC6A4solute carrier family 6 member 49031CGNC:3120Inparanoid, OMA, EggNOG
Anole lizard100562250slc6a4solute carrier family 6 member 428377Inparanoid, OMA, EggNOG
Zebrafish664719slc6a4asolute carrier family 6 (neurotransmitter transporter), member 4a7955ZDB-GENE-060314-1Inparanoid, OMA
C. elegans171879mod-5Transporter6239Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Sodium-dependent serotonin transporter
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC6 neurotransmitter transporter family    /    Monoamine transporter subfamily    /    Sodium-dependent serotonin transporter

Associated Recombinant Proteins

NomSpecification and purityExpression systemProtein labelDisponibilitéVoir les détails

Associated Antibodies

NomSpecificationsSpecies reactivityApplicationDisponibilitéVoir les détails

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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