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SCN8A

DescriptionSodium channel protein type 8 subunit alpha

Gene and Protein Information

Gene ID6334
Uniprot Accession IDs Q9UQD0 B9VWG8 O95788 Q9NYX2 Q9UPB2
Ensembl ID ENSP00000346534
Symbole MED MED PN4 CIAT BFIS5 NaCh6 CERIII EIEE13 MYOCL2 Nav1.6
FamilyBelongs to the sodium channel (TC 1.A.1.10) family. Nav1.6/SCN8A subfamily.
Sequence
MAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGSRSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEESQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLARRGFICKKTTSNKLENGGTHREKKESTPSTASLPSYDSVTKPEKEKQQRAEEGRRERAKRQKEVRESKC
Afficher plus
Homologous gene and protein info.
SpeciesGene IDGene SymbolNomNuméro d'identification fiscale Other Gene IDSources
Macaque695972SCN8Asodium voltage-gated channel alpha subunit 89544Inparanoid, OMA, EggNOG
Mouse20273Scn8asodium channel, voltage-gated, type VIII, alpha10090MGI:103169Inparanoid, OMA, EggNOG
Rat29710Scn8asodium voltage-gated channel alpha subunit 810116RGD:3638Inparanoid, OMA, EggNOG
Dog477604SCN8Asodium voltage-gated channel alpha subunit 89615VGNC:45923Inparanoid, OMA
Horse100052777SCN8Asodium voltage-gated channel alpha subunit 89796VGNC:22742Inparanoid, OMA
Cow537277SCN8Asodium voltage-gated channel alpha subunit 89913VGNC:34354Inparanoid, OMA
Anole lizard100556690scn8asodium voltage-gated channel alpha subunit 828377Inparanoid, OMA
Xenopus549640scn8asodium channel, voltage gated, type VIII alpha subunit8364XB-GENE-1011299Inparanoid, OMA
Zebrafish58152scn8aasodium channel, voltage gated, type VIII, alpha subunit a7955ZDB-GENE-000828-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    calcium channel    /    Sodium channel protein type 8 subunit alpha
protein    /    transporter    /    voltage-gated sodium channel    /    Sodium channel protein type 8 subunit alpha
protein    /    transporter    /    voltage-gated calcium channel    /    Sodium channel protein type 8 subunit alpha
protein    /    transporter    /    sodium channel    /    Sodium channel protein type 8 subunit alpha
protein    /    transporter    /    voltage-gated ion channel    /    Sodium channel protein type 8 subunit alpha
DTO Classes
protein    /    Ion channel    /    Sodium channel family    /    Nav1.6/SCN8A subfamily    /    Sodium channel protein type 8 subunit alpha

Associated Recombinant Proteins

NomSpecification and purityExpression systemProtein labelDisponibilitéVoir les détails

Associated Antibodies

NomSpecificationsSpecies reactivityApplicationDisponibilitéVoir les détails

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomDirect Associated TargetsDisease TypeMondoid

      Bibliography

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