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| Description | Serine/threonine-protein kinase PLK4 |
|---|
Gene and Protein Information
| Gene ID | 10733 |
|---|---|
| Uniprot Accession IDs | O00444 B2RAL0 B7Z837 B7Z8G7 Q8IYF0 Q96Q95 Q9UD84 Q9UDE2 |
| Ensembl ID | ENSP00000270861 |
| Symbole | SAK STK18 SAK STK18 MCCRP2 |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. |
| Sequence | MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH Afficher plus |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Nom | Numéro d'identification fiscale | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 461480 | PLK4 | polo like kinase 4 | 9598 | VGNC:7051 | OMA, EggNOG |
| Macaque | 710233 | PLK4 | polo like kinase 4 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20873 | Plk4 | polo like kinase 4 | 10090 | MGI:101783 | Inparanoid, OMA, EggNOG |
| Rat | 310344 | Plk4 | polo-like kinase 4 | 10116 | RGD:1305390 | Inparanoid, OMA, EggNOG |
| Dog | 476087 | PLK4 | polo like kinase 4 | 9615 | VGNC:44698 | Inparanoid, OMA, EggNOG |
| Horse | 100063593 | PLK4 | polo like kinase 4 | 9796 | VGNC:21582 | Inparanoid, OMA, EggNOG |
| Cow | 514405 | PLK4 | polo like kinase 4 | 9913 | VGNC:33036 | Inparanoid, OMA, EggNOG |
| Opossum | 100010836 | PLK4 | polo like kinase 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 422497 | PLK4 | polo like kinase 4 | 9031 | CGNC:51756 | OMA, EggNOG |
| Anole lizard | 100557501 | plk4 | polo like kinase 4 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100038180 | plk4 | polo like kinase 4 | 8364 | XB-GENE-493608 | Inparanoid, OMA, EggNOG |
| Zebrafish | 368390 | plk4 | polo-like kinase 4 (Drosophila) | 7955 | ZDB-GENE-030619-14 | Inparanoid, OMA, EggNOG |
| Fruitfly | 40384 | SAK | Sak kinase | 7227 | FBgn0026371 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / Other group / PLK family / Serine/threonine-protein kinase plk4
protein / Kinase / Protein kinase / Other group / PLK family / Serine/threonine-protein kinase plk4
Associated Recombinant Proteins
| Nom | Specification and purity | Expression system | Protein label | Disponibilité | Voir les détails |
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Associated Antibodies
| Nom | Spécifications | Species reactivity | Application | Disponibilité | Voir les détails |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Nom | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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