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· · COA & SDS disponible pour chaque produit · Expédition le jour même sur les articles en stock TCN 238 - Moligand™, ≥98%(HPLC) , Allosteric modulator of mGlu 4 receptor, CAS No.125404-04-8, Allosteric modulator of mGlu 4 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
BDBM50323546 | AKOS000278717 | MS-23068 | 4-[(1E)-2-phenylethenyl]pyrimidin-2-amine | GTPL6235 | Lu AF32615 | TCN 238 | 4-((e)-styryl)-pyrimidin-2-ylamine | 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4h-chromen-4-one | HY-14419 | J-005224 |
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonymes
BDBM50323546 | AKOS000278717 | MS-23068 | 4-[(1E)-2-phenylethenyl]pyrimidin-2-amine | GTPL6235 | Lu AF32615 | TCN 238 | 4-((e)-styryl)-pyrimidin-2-ylamine | 3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4h-chromen-4-one | HY-14419 | J-005224 |
Spécifications et pureté
Moligand™, ≥98%(HPLC)
Mécanismes biochimiques et physiologiques
Positive allosteric modulator of mGlu4receptors (EC50= 1.0μM for human and rat mGlu4receptors). Orally available and brain penetrant.
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
ALLOSTERIC MODULATOR
Mécanisme d'action
Allosteric modulator of mGlu 4 receptor
Noms et identifiants Sourires canoniques
C1=CC=C(C=C1)C=CC2=NC(=NC=C2)N
IUPAC Name
4-[(E)-2-phenylethenyl]pyrimidin-2-amine
InChIKey
LNUXNUNUGIHCPA-VOTSOKGWSA-N
INCHI
1S/C12H11N3/c13-12-14-9-8-11(15-12)7-6-10-4-2-1-3-5-10/h1-9H,(H2,13,14,15)/b7-6+
Isomères SMILES
C1=CC=C(C=C1)/C=C/C2=NC(=NC=C2)N
CAS alternatif
125404-04-8
Termes d'entrée MeSH
3-cyclohexyl-5-fluoro-6-methyl-7-(2-morpholin-4-ylethoxy)-4H-chromen-4-one;CFMMC cpd
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Styrenes Intermediate Tree Nodes Not available Direct Parent Styrenes Alternative Parents Aminopyrimidines and derivatives Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Styrene - Aminopyrimidine - Pyrimidine - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Solubilité Solvent:DMSO, Max Conc. mg/mL: 19.72, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 1.97, Max Conc. mM: 10 Poids moléculaire 197.240 g/mol XLogP3 2.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 2 Exact Mass 197.095 Da Monoisotopic Mass 197.095 Da Topological Polar Surface Area 51.800 Ų Heavy Atom Count 15 Formal Charge 0 Complexity 209.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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