Thioperamide maleate - ≥98% , CAS No.148440-81-7

CAS: 148440-81-7 Cat. No.: T274684 Formule: C₁₅H₂₄N₄S.C₄H₄O₄ Poids moléculaire: 408.51 Numéro CE: 622-519-7 PubChem CID: 11211984

GRADE & PURITY ≥98%

Synonyms

SR-01000075293-3 | SR-01000075293-1 | 5-(4-Bromophenyl)-1H-tetrazole, 97% | CCG-220922 | NSC-749330 | DTXSID501017661 | SCHEMBL17908154 | J-008468 | THIOPERAMIDEMALEATE | CCG-222518 | SMR000326909 | N-cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioa

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonymes

SR-01000075293-3 | SR-01000075293-1 | 5-(4-Bromophenyl)-1H-tetrazole, 97% | CCG-220922 | NSC-749330 | DTXSID501017661 | SCHEMBL17908154 | J-008468 | THIOPERAMIDEMALEATE | CCG-222518 | SMR000326909 | N-cyclohexyl-4-(1H-imidazol-4-yl)-1-piperidinecarbothioa

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

Potent, selective H 3 antagonist that crosses the blood-brain barrier.

Conditions de stockage de stockage

Store at -20°C,Desiccated

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥98%

Noms et identifiants

• Sourires canoniques: C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3.C(=CC(=O)O)C(=O)O
• IUPAC Name: (Z)-but-2-enedioic acid;N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
• InChIKey: WUYMIKDBRCCYGE-BTJKTKAUSA-N
• INCHI: 1S/C15H24N4S.C4H4O4/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14;5-3(6)1-2-4(7)8/h10-13H,1-9H2,(H,16,17)(H,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1-
• Isomères SMILES: C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3.C(=C\C(=O)O)\C(=O)O
• PubChem CID: 11211984
• Poids moléculaire: 408.51

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Unsaturated fatty acids Dicarboxylic acids and derivatives Imidazoles Heteroaromatic compounds Thioureas Carboxylic acids Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: Dicarboxylic acid or derivatives - Piperidine - Unsaturated fatty acid - Fatty acid - Fatty acyl - Azole - Imidazole - Heteroaromatic compound - Thiourea - Azacycle - Carboxylic acid - Carboxylic acid derivative - Carbonyl group - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

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TRPV1 Tclin Vanilloid receptor (8273 Activities)

Discover Target: TRPV1

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

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BLM Tchem Bloom syndrome protein (4248 Activities)

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GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

Discover Target: RUNX1

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Plasmodium falciparum (966862 Activities)

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nfo Endonuclease 4 (425 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in water to 50 mM
• Poids moléculaire: 408.500 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 408.183 Da
• Monoisotopic Mass: 408.183 Da
• Topological Polar Surface Area: 151.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 441.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 2

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