trans-4-Hydroxycrotonic acid - ≥98% , CAS No.24587-49-3

CAS: 24587-49-3 Cat. No.: T341890 Formule: C₄H₆O₃ Poids moléculaire: 102.09 Numéro CE: 807-669-5 PubChem CID: 6155526

GRADE & PURITY ≥98%

Synonyms

(2E)-4-hydroxybut-2-enoic acid | 2-Butenoic acid, 4-hydroxy- | DTXCID504334 | BBL102925 | 4-Hydroxycrotonic acid | 4-hydroxy-crotonic acid | 4-HYDROXY-BUT-2-ENOICACID | 4-hydroxybut-2-enoicacid | T-HCA | BCP21499 | trans-4-hydroxycrotonic-acid | EC 233-26

Storage

Store at 2-8°C,Argon charged,Desiccated

Shipped In

Wet ice

Vue d’ensemble

trans-4-Hydroxycrotonic acid binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. It may be an endogenous ligand.

Specifications

Synonymes

(2E)-4-hydroxybut-2-enoic acid | 2-Butenoic acid, 4-hydroxy- | DTXCID504334 | BBL102925 | 4-Hydroxycrotonic acid | 4-hydroxy-crotonic acid | 4-HYDROXY-BUT-2-ENOICACID | 4-hydroxybut-2-enoicacid | T-HCA | BCP21499 | trans-4-hydroxycrotonic-acid | EC 233-26

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Store at 2-8°C,Argon charged,Desiccated

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Propriétés du produit

• pKa: pKₐ: 4.31 (Predicted)
• Ki Data: Displacement of [3H]NCS-382 from GABAB receptor in rat brain homogenate: Ki= 1 μM (rat)

Noms et identifiants

• Pubchem Sid: 504764026
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764026
• Sourires canoniques: C(C=CC(=O)O)O
• IUPAC Name: (E)-4-hydroxybut-2-enoic acid
• InChIKey: RMQJECWPWQIIPW-OWOJBTEDSA-N
• INCHI: 1S/C4H6O3/c5-3-1-2-4(6)7/h1-2,5H,3H2,(H,6,7)/b2-1+
• Isomères SMILES: C(/C=C/C(=O)O)O
• PubChem CID: 6155526
• Poids moléculaire: 102.09

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroxy fatty acids
• Alternative Parents: Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hydroxy fatty acid - Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group.
• External Descriptors: Hydroxy fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (non humaines)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in DMSO (100 mM).
• Sensibilité: Moisture sensitive；light sensitive
• Indice de réfraction: n20D1.50 (Predicted)
• Point d'ébullition (°C): ~338.75° C at 760 mmHg (Predicted)
• Point de fusion (°C): 45.99° C (Predicted)
• Poids moléculaire: 102.090 g/mol
• XLogP3: -0.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 102.032 Da
• Monoisotopic Mass: 102.032 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 84.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 24587-49-3, the molecular formula is C4H6O3, and the molecular weight is 102.09 g/mol. InChIKey RMQJECWPWQIIPW-OWOJBTEDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.