USP7/USP47 inhibitor - 10mM in DMSO , CAS No.1247825-37-1

CAS: 1247825-37-1 Cat. No.: U656523 Formule: C₁₈H₁₁Cl₂N₃O₃S₃ Poids moléculaire: 484.4 PubChem CID: 51031028

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC 50 s of 0.42 μM and 1.0 μM, respectively.

In Vitro

USP7/USP47 inhibitor (compound 14) is a selective inhibitor of USP7/USP47 with EC 50 s of 0.42 μM and 1 μM, respectively. USP7/USP47 inhibitor does not inhibit caspase 3, calpain 1, 20S proteasome, and a panel of representative USPs (USP2, USP5, USP8, USP21, and USP28; EC 50 > 31.6 μM). USP7/USP47 inhibitor inhibits the growth of HCT-116 cells with an EC 50 of 7.6 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:EC50: 0.42 μM (USP7), 1.0 μM (USP47)

Specifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC 50 s of 0.42 μM and 1.0 μM, respectively.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

• Isomères SMILES: CS(=O)(=O)C1=CC=C(C=C1)NC(=O)C2=CC(=C(S2)SC3=C(C=NC=C3Cl)Cl)C#N
• PubChem CID: 51031028
• Poids moléculaire: 484.4

Cibles associées (humaines)

USP7 Tchem Ubiquitin carboxyl-terminal hydrolase 7 (0 Activities)

Discover Target: USP7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

USP47 Tchem Ubiquitin carboxyl-terminal hydrolase 47 (0 Activities)

Discover Target: USP47

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Foire aux questions

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1247825-37-1, the molecular formula is C18H11Cl2N3O3S3, and the molecular weight is 484.4 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.