Valproic acid-d15 - ≥99%,≥99 atom% D , CAS No.362049-65-8

CAS: 362049-65-8 Cat. No.: V650220 Formule: C₈HD₁₅O₂ Poids moléculaire: 159.30

GRADE & PURITY ≥99%,≥99 atom% D

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Specifications

Spécifications et pureté

≥99%,≥99 atom% D

Mécanismes biochimiques et physiologiques

Valproic acid-d 15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor , with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2 . Valpro

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%,≥99 atom% D

Noms et identifiants

• Pubchem Sid: 528767684
• Isomères SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C(=O)O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
• CAS alternatif: 99-66-1(unlabelled)
• Poids moléculaire: 159.30