Name: Varespladib - Moligand™, ≥98% , Phospholipase A2 group IIA inhibitor, CAS No.172732-68-2, Phospholipase A2 group IIA inhibitor
Brand: Aladdin Scientific
SKU: V125011
Availability: InStock

Varespladib - Moligand™, ≥98% , Phospholipase A2 group IIA inhibitor, CAS No.172732-68-2, Phospholipase A2 group IIA inhibitor

CAS: 172732-68-2 Cat. No.: V125011 Formule: C₂₁H₂₀N₂O₅ Poids moléculaire: 380.39 PubChem CID: 155815

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Varespladib - Moligand™, ≥98% CAS No(172732-68-2) by Aladdin Scientific

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DISPONIBLE À COMMANDE

QUALITÉ & PURETÉ Moligand™ ? ≥98%

Synonyms

2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid | DTXSID50169378 | 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetic acid | A-001 | EN300-19110 | NCGC00346491-08 | FT-0659937 | Varespladib [USAN] | SB16

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Fiche de spécifications

Vue d’ensemble Spécifications Propriétés du produit Noms et identifiants Documentation Données avancées Taxonomic Classification Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Calculateurs de solution Avis

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Pourquoi cette qualité

Moligand™, ≥98% Moligand™ pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.

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Stockage & expédition

Store at -20°C Expédition Ice chest + Ice pads. Consultez le COA spécifique au lot pour les spécifications exactes.

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Documents qualité

SDS, COA, fiche technique et fiche de spécifications disponibles au téléchargement. COA spécifique au lot accessible via la recherche par numéro de lot.

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Preuve documentaire

Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.

Vue d’ensemble

Varespladib (LY315920) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM.

Spécifications

Synonymes

Spécifications et pureté

Moligand™, ≥98%

Mécanismes biochimiques et physiologiques

Varespladib (LY 315920), a specifically designed indolic secretory phospholipase A2 (sPLA2) inhibitor, has shown promising results in animals and adults. Inhibition seems to be inversely related to the severity of gas exchange impairment.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Mécanisme d'action

Phospholipase A2 group IIA inhibitor

Pureté

≥98%

Propriétés du produit

ALogP

2.8

Noms et identifiants

Pubchem Sid

528769948

Sourires canoniques

CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N

IUPAC Name

2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid

InChIKey

BHLXTPHDSZUFHR-UHFFFAOYSA-N

INCHI

1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)

Isomères SMILES

CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N

WGK Allemagne

PubChem CID

155815

Poids moléculaire

380.39

Documentation

📋 Fiche de données de sécurité (FDS)

Document complet couvrant les dangers, la manipulation, le stockage et la conformité réglementaire.

<<<<<<< HEAD Télécharger la SDS → ======= Télécharger la SDS → >>>>>>> release248-p3

✅ Certificat d'analyse (COA)

Données qualité spécifiques au lot. Saisissez votre numéro de lot pour récupérer le COA exact.

Rechercher le COA →

📊 Fiche technique

Résumé de référence rapide des spécifications et applications du produit.

Voir la fiche technique →

🔬 Fiche de spécifications

Attributs de qualité complets et critères d'acceptation pour cette qualité.

Voir la fiche de spécifications →

Données avancées

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Classe Benzene and substituted derivatives
    - Subclass Phenoxyacetic acid derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Classe	Benzene and substituted derivatives
Subclass	Phenoxyacetic acid derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Phenoxyacetic acid derivatives
Alternative Parents	N-alkylindoles Indoles Aryl ketones Alkyl aryl ethers Substituted pyrroles Vinylogous amides Heteroaromatic compounds Primary carboxylic acid amides Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Phenoxyacetate - N-alkylindole - Indole - Indole or derivatives - Aryl ketone - Alkyl aryl ether - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Vinylogous amide - Carboxamide group - Ketone - Primary carboxylic acid amide - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Carboxylic acid - Ether - Monocarboxylic acid or derivatives - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxide - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as phenoxyacetic acid derivatives. These are compounds containing an anisole where the methane group is linked to an acetic acid or a derivative.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Structure 3D

Cibles associées (humaines)

PLA2G2D Tchem Group IID secretory phospholipase A2 (1 Activities)

Discover Target: PLA2G2D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G6 Tchem 85/88 kDa calcium-independent phospholipase A2 (7 Activities)

Discover Target: PLA2G6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G1B Tchem Phospholipase A2 (3 Activities)

Discover Target: PLA2G1B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G10 Tchem Group 10 secretory phospholipase A2 (6 Activities)

Discover Target: PLA2G10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2F Tchem Group IIF secretory phospholipase A2 (1 Activities)

Discover Target: PLA2G2F

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2A Tchem Phospholipase A2, membrane associated (10 Activities)

Discover Target: PLA2G2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G5 Tchem Calcium-dependent phospholipase A2 (3 Activities)

Discover Target: PLA2G5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2E Tchem Group IIE secretory phospholipase A2 (2 Activities)

Discover Target: PLA2G2E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)

Discover Target: PLA2G2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2E Tchem Group IIE secretory phospholipase A2 (20 Activities)

Discover Target: PLA2G2E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G10 Tchem Group X secretory phospholipase A2 (219 Activities)

Discover Target: PLA2G10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G6 Tchem Calcium-independent phospholipase A2 (359 Activities)

Discover Target: PLA2G6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2F Tchem Group IIF secretory phospholipase A2 (15 Activities)

Discover Target: PLA2G2F

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2D Tchem Group IID secretory phospholipase A2 (24 Activities)

Discover Target: PLA2G2D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G5 Tchem Phospholipase A2 group V (238 Activities)

Discover Target: PLA2G5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G3 Tbio Group III secretory phopholipase A2 (31 Activities)

Discover Target: PLA2G3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G12A Tbio Group XIIA secretory phospholipase A2 (16 Activities)

Discover Target: PLA2G12A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

PLA2G1B Phospholipase A2 group 1B (227 Activities)

Discover Target: PLA2G1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cavia porcellus (23802 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2A Phospholipase A2, membrane associated (2 Activities)

Discover Target: PLA2G2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Date	Article
A1917103	Certificate of Analysis	Mar 20, 2026	V125011
A1917102	Certificate of Analysis	Mar 20, 2026	V125011

Propriétés chimiques et physiques

Solubilité	DMSO 76 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Poids moléculaire	380.400 g/mol
XLogP3	2.800
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	380.137 Da
Monoisotopic Mass	380.137 Da
Topological Polar Surface Area	112.000 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	589.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Calculateurs de solution

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Dilution Calculator

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Reconstitution Calculator

Avis

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Voir le guide des qualités Moligand™ →

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Varespladib - Moligand™, ≥98% , Phospholipase A2 group IIA inhibitor, CAS No.172732-68-2, Phospholipase A2 group IIA inhibitor

Stockage & expédition

Documents qualité

Preuve documentaire

Vue d’ensemble

Spécifications

Documentation

📋 Fiche de données de sécurité (FDS)

✅ Certificat d'analyse (COA)

📊 Fiche technique

🔬 Fiche de spécifications

Données avancées

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Avis des clients

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