WIN 54954 - 10mM in DMSO , CAS No.107355-45-3

CAS: 107355-45-3 Cat. No.: W655912 Formule: C₁₈H₂₀Cl₂N₂O₃ Poids moléculaire: 383.27 PubChem CID: 441048

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.

In Vitro

WIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL).\nWIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC 80 of 0.06 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.

Conditions de stockage de stockage

Protected from light,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

• Isomères SMILES: CC1=NOC(=C1)CCCCCOC2=C(C=C(C=C2Cl)C3=NCCO3)Cl
• PubChem CID: 441048
• Poids moléculaire: 383.27