XMD16-5 - ≥99% , CAS No.1345098-78-3
En stock
SKU
X413957
ACK Inhibitors
Information
XMD16-5 XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.
Targets
TNK2
In vitro
XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
Cell Research(from reference)
Cell lines：293T cells
Concentrations：10 nM-5 μM
Incubation Time：6 h
Plus d’information
| CAS | 1345098-78-3 |
|---|---|
| Synonymes | 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one,5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl- |
| Spécifications et pureté | ≥99% |
| Conditions de stockage de stockage | Store at -20°C |
| Expédié en | Ice chest + Ice pads |
| Product Description | Information XMD16-5 XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations. Targets TNK2 In vitro XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types. Cell Research(from reference) Cell lines：293T cells Concentrations：10 nM-5 μM Incubation Time：6 h |
| Pubchem Sid | 488201820 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201820 |
| Solubilité | Solubility (25°C) In vitro DMSO: 83 mg/mL (199.28 mM); Ethanol: 5 mg/mL (12.0 mM); Water: Insoluble; |
| Cible | TNK2 |
| PubChem CID | 57340666 |
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