Via MAPK/ERK - proteina chinasi 3 attivata dal mitogeno Supplier | High Purity

Prodotti popolari

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CP 43
CAS: 850467-66-2 Formula: C₂₅H₂₄N₂O₂ Peso molecolare: 384.47

10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C426251
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N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide

SMILES

C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4

InChIKey
WQKXOAJVNFOHNZ-UHFFFAOYSA-N

InChI

1S/C25H24N2O2/c28-24(27-23-12-6-10-20-9-4-5-11-22(20)23)17-26-25(29)21-15-13-19(14-16-21)18-7-2-1-3-8-18/h1-5,7-9,11,13-16,23H,6,10,12,17H2,(H,26,29)(show more

Sinonimi
N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide
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CP 43
CAS: 850467-66-2 Formula: C₂₅H₂₄N₂O₂ Peso molecolare: 384.47

≥98%(HPLC)

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C287360
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N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide

SMILES

C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4

InChIKey
WQKXOAJVNFOHNZ-UHFFFAOYSA-N

InChI

1S/C25H24N2O2/c28-24(27-23-12-6-10-20-9-4-5-11-22(20)23)17-26-25(29)21-15-13-19(14-16-21)18-7-2-1-3-8-18/h1-5,7-9,11,13-16,23H,6,10,12,17H2,(H,26,29)(show more

Sinonimi
N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide | TAO Kinase inhibitor 1
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Demethyl-Coclaurine
CAS: 5843-65-2 Formula: C₁₆H₁₇NO₃ Peso molecolare: 271.31

10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D424889
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1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol

SMILES

C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O

InChIKey
WZRCQWQRFZITDX-UHFFFAOYSA-N

InChI

1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2

Sinonimi
6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
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Demethyl-Coclaurine
CAS: 5843-65-2 Formula: C₁₆H₁₇NO₃ Peso molecolare: 271.31

≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D412891
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1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol

SMILES

C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O

InChIKey
WZRCQWQRFZITDX-UHFFFAOYSA-N

InChI

1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2

Sinonimi
6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
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GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5
CAS: 1262041-49-5 Formula: C₂₃H₂₁N₇O Peso molecolare: 411.46

Moligand™ ? 10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G421098
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4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide

SMILES

C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6

InChIKey
ZGCMQKWOUIMBEP-UHFFFAOYSA-N

InChI

1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)

Sinonimi
GS444217 | GS 444217 | ASK1-IN-1
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GSK 114
CAS: 1301761-96-5 Formula: C₁₉H₂₃N₅O₄S Peso molecolare: 417.48

Solido Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G412389
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3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamide

SMILES

CNS(=O)(=O)C1=CC(=C(C=C1)N(C)C)NC2=NC=NC3=CC(=C(C=C32)OC)OC

InChIKey
YUSROMRPOFFTMX-UHFFFAOYSA-N

InChI

1S/C19H23N5O4S/c1-20-29(25,26)12-6-7-16(24(2)3)15(8-12)23-19-13-9-17(27-4)18(28-5)10-14(13)21-11-22-19/h6-11,20H,1-5H3,(H,21,22,23)

Sinonimi
GSK-114 | 3-((6,7-Dimethoxyquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamide
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GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5
CAS: 1262041-49-5 Formula: C₂₃H₂₁N₇O Peso molecolare: 411.46

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G412159
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4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide

SMILES

C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6

InChIKey
ZGCMQKWOUIMBEP-UHFFFAOYSA-N

InChI

1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)

Sinonimi
GS444217 | GS 444217 | ASK1-IN-1
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Higenamine hydrochloride
CAS: 11041-94-4 Formula: C₁₆H₁₇NO₃.HCl Peso molecolare: 307.77

10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: H420598
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1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride

SMILES

C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl

InChIKey
SWWQQSDRUYSMAR-UHFFFAOYSA-N

InChI

1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H

Sinonimi
6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
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Higenamine hydrochloride
CAS: 11041-94-4 Numero EC: 802-566-1 Formula: C₁₆H₁₇NO₃.HCl Peso molecolare: 307.77

Solido ≥99%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: H413084
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1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride

SMILES

C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl

InChIKey
SWWQQSDRUYSMAR-UHFFFAOYSA-N

InChI

1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H

Sinonimi
6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
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N-Des(aminocarbonyl) AZ-TAK1 inhibitor
CAS: 494772-87-1 Formula: C₁₆H₁₉N₃O₂S Peso molecolare: 317.41

◐ .Su ordinazione · 8–12 settimane Oggetto #: D275539
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3-amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide

SMILES

C1COCCN1CC2=CC=C(C=C2)C3=CC(=C(S3)C(=O)N)N

InChIKey
UNTPTSFVGRSTDC-UHFFFAOYSA-N

InChI

1S/C16H19N3O2S/c17-13-9-14(22-15(13)16(18)20)12-3-1-11(2-4-12)10-19-5-7-21-8-6-19/h1-4,9H,5-8,10,17H2,(H2,18,20)

Sinonimi
3-Amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide | N-Des(aminocarbonyl) AZ-TAK1 Inhibitor | starbld0...
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NG25, Inhibitor of C-terminal Src kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of mitogen-activated protein kinase kinase kinase 7;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of SRC proto-oncoge
CAS: 1315355-93-1 Numero EC: 110-114-3 Formula: C₂₉H₃₀F₃N₅O₂ Peso molecolare: 537.58

Moligand™ ? 10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: N421221
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N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

SMILES

CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F

InChIKey
SMPGEBOIKULBCT-UHFFFAOYSA-N

InChI

1S/C29H30F3N5O2/c1-3-36-12-14-37(15-13-36)18-21-6-7-22(17-24(21)29(30,31)32)35-28(38)20-5-4-19(2)26(16-20)39-25-9-11-34-27-23(25)8-10-33-27/h4-11,16-1show more

Sinonimi
AC-35824 | Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]py...
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NQDI 1
CAS: 175026-96-7 Formula: C₁₉H₁₃NO₄ Peso molecolare: 319.31

10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: N422144
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ethyl 8,15-dioxo-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-16-carboxylate

SMILES

CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O

InChIKey
UFJGFNHRMPMALC-UHFFFAOYSA-N

InChI

1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)

Sinonimi
2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester; ethyl 2,7-dioxo-3,7-dihydro-2H-nap...

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Domande frequenti

How is the MAP3K listing put together?

It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a MAP3K modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for MAP3K compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the MAP3K compound I need is not listed?

Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.