proteina chinasi 3 attivata dal mitogeno

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  1. 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
    CAS: 173043-84-0 PubChem CID: 1607 Formula: C7H8N2O3 Peso molecolare: 168.15
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: D667774
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    Nome IUPAC
    N-(3,4-dihydroxyphenyl)-N-methylnitrous amide
    SMILES
    CN(C1=CC(=C(C=C1)O)O)N=O
    InChIKey
    XAKAQCMEMMZUEO-UHFFFAOYSA-N
    InChI
    1S/C7H8N2O3/c1-9(8-12)5-2-3-6(10)7(11)4-5/h2-4,10-11H,1H3
    Sinonimi
    3,4-dephostatin | Me-3,4-dephostatin | Methyl-3,4-dephostatin | 3,4-Dihydroxy-N-methyl-N-nitrosoaniline | 4-[methyl(N...
  2. N-[5-(isopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide
    CAS: 1124381-69-6 PubChem CID: 59437537
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: N1330315
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    Nome IUPAC
    N-[5-(propan-2-ylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]pyridine-3-carboxamide
    SMILES
    CC(C)NC1=CC(=CC2=NC(=NN12)NC(=O)C3=CN=CC=C3)C(F)(F)F
    InChIKey
    BDAJJFZKNIYDOL-UHFFFAOYSA-N
    InChI
    1S/C16H15F3N6O/c1-9(2)21-12-6-11(16(17,18)19)7-13-22-15(24-25(12)13)23-14(26)10-4-3-5-20-8-10/h3-9,21H,1-2H3,(H,23,24,26)
  3. 3-((6-((5-Chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
    CAS: 1316059-00-3 PubChem CID: 68304261
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: C980498
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    Nome IUPAC
    3-[[6-[(5-chloropyridin-2-yl)amino]pyrimidin-4-yl]amino]-4-ethylsulfonyl-N-methylbenzenesulfonamide
    SMILES
    CCS(=O)(=O)C1=C(C=C(C=C1)S(=O)(=O)NC)NC2=NC=NC(=C2)NC3=NC=C(C=C3)Cl
    InChIKey
    OEDGERSSZUMLBI-UHFFFAOYSA-N
    InChI
    1S/C18H19ClN6O4S2/c1-3-30(26,27)15-6-5-13(31(28,29)20-2)8-14(15)24-17-9-18(23-11-22-17)25-16-7-4-12(19)10-21-16/h4-11,20H,3H2,1-2H3,(H2,21,22,23,24,25show more
  4. 7,3',4'-Trihydroxyisoflavone
    CAS: 485-63-2 Numero EC: 676-470-1 PubChem CID: 5284648 Formula: C15H10O5 Peso molecolare: 270.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: T1495666
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  5. ASK1-IN-6
    CAS: 2407451-82-3 Formula: C17H14F4N6O2 Peso molecolare: 410.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: A1498430
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  6. GSK854
    CAS: 1316059-00-3 PubChem CID: 68304261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: G1495212
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  7. GSK329
    CAS: 1268490-12-5 Formula: C19H14Cl2F3N5O2 Peso molecolare: 472.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: G1495064
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  8. Pelubiprofen
    CAS: 69956-77-0 PubChem CID: 5282203
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: P1495552
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  9. Tpl2 Kinase Inhibitor 1
    CAS: 871307-18-5 Numero EC: 111-094-9 PubChem CID: 9549300 Formula: C21H14ClFN6 Peso molecolare: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: T1495533
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  10. TAK1-IN-3
    CAS: 494772-87-1 Formula: C16H19N3O2S Peso molecolare: 317.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: T1494952
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  11. TC ASK 10
    CAS: 1005775-56-3 PubChem CID: 68661090 Formula: C21H21N5O.2HCl Peso molecolare: 432.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: T1493633
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Domande frequenti

How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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