Panoramica Specifications Nomi e identificatori Documentazione Advanced Data Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Domande frequenti e articoli Citations of This Product Calcolatori di soluzioni Recensioni

🧪

Why this grade

UltraPureChrom™, for GC-HS for GC-HS,UltraPureChrom™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9509 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all residual solvents defined by the ICH.

Application

Solvent for many hydrophobic organic compounds.

Specifications

Sinonimi

Formyldimethylamine | DMF | NSC 5356

Specifiche e purezza

UltraPureChrom™, for GC-HS

Condizioni di conservazione di stoccaggio

Room temperature

Spedito in

FedEx DG Service

Grado

for GC-HS, UltraPureChrom™

Nomi e identificatori

Pubchem Sid

504751033

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751033

Sorrisi canonici

CN(C)C=O

IUPAC Name

N,N-dimethylformamide

InChIKey

ZMXDDKWLCZADIW-UHFFFAOYSA-N

INCHI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

Isomeri SMILES

CN(C)C=O

WGK Germania

RTECS

LQ2100000

Numero UN

2265

Gruppo di imballaggio

III

Peso molecolare

73.09

Beilstein

605365

Reaxy-Rn

605365

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=605365&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Classe Carboxylic acids and derivatives
    - Subclass Carboxylic acid derivatives
      - Level5 Carboxylic acid amides
        Level6 Tertiary carboxylic acid amides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Classe	Carboxylic acids and derivatives
Subclass	Carboxylic acid derivatives
Intermediate Tree Nodes	Carboxylic acid amides
Direct Parent	Tertiary carboxylic acid amides
Alternative Parents	Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Tertiary carboxylic acid amide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
Descrizione	This compound belongs to the class of organic compounds known as tertiary carboxylic acid amides. These are compounds containing an amide derivative of carboxylic acid, with the general structure RN(R1)C(R2)=O (R1-R2 any atom but H).
External Descriptors	a small molecule
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)

Discover Target: PDE5A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

Discover Target: EGFR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA2 Tclin Carbonic anhydrase II (17698 Activities)

Discover Target: CA2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HMGCR Tclin HMG-CoA reductase (2475 Activities)

Discover Target: HMGCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

INSR Tclin Insulin receptor (5558 Activities)

Discover Target: INSR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

Discover Target: ADRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

Discover Target: CHRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

Discover Target: HTR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

Discover Target: CHRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD2 Tclin Dopamine D2 receptor (23596 Activities)

Discover Target: DRD2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD1 Tclin Dopamine D1 receptor (9720 Activities)

Discover Target: DRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD4 Tchem Dopamine D4 receptor (7907 Activities)

Discover Target: DRD4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

Discover Target: SLC6A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH2 Tclin Histamine H2 receptor (5428 Activities)

Discover Target: HRH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)

Discover Target: ADRA1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)

Discover Target: HTR1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

Discover Target: HTR2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

Discover Target: HTR2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CALCR Tclin Calcitonin receptor (2215 Activities)

Discover Target: CALCR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A4 Tclin Serotonin transporter (12625 Activities)

Discover Target: SLC6A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

Discover Target: ADRA1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH1 Tclin Histamine H1 receptor (7573 Activities)

Discover Target: HRH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)

Discover Target: ADRA1B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DRD3 Tclin Dopamine D3 receptor (14368 Activities)

Discover Target: DRD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)

Discover Target: AVPR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

Discover Target: OPRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRK1 Tclin Kappa opioid receptor (16155 Activities)

Discover Target: OPRK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC6A3 Tclin Dopamine transporter (10535 Activities)

Discover Target: SLC6A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)

Discover Target: HTR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR2 Tclin Estrogen receptor beta (9272 Activities)

Discover Target: ESR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)

Discover Target: CYSLTR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)

Discover Target: ERBB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)

Discover Target: CHRM4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)

Discover Target: CHRM5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

Discover Target: Agtr2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mc4r Melanocortin receptor 4 (1205 Activities)

Discover Target: Mc4r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ltc4s Leukotriene C4 synthase (1 Activities)

Discover Target: Ltc4s

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sigmar1 Sigma opioid receptor (160 Activities)

Discover Target: Sigmar1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Npy1r Neuropeptide Y receptor type 1 (8 Activities)

Discover Target: Npy1r

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

Discover Target: Cckar

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus (868 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aspergillus niger (16508 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Fusarium oxysporum (3998 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus capitis (242 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Macrophomina phaseolina (474 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Impa1 Inositol monophosphatase 1 (16203 Activities)

Discover Target: Impa1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Glra2 Glycine receptor (1745 Activities)

Discover Target: Glra2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Certificati (CoA, COO, BSE/TSE e tabella di analisi)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot Number	Certificate Type	Data	Oggetto
I2615603	Certificate of Analysis	Sep 01, 2026	N433309
I2615604	Certificate of Analysis	Sep 01, 2026	N433309
I2615605	Certificate of Analysis	Sep 01, 2026	N433309
E2614124	Certificate of Analysis	Apr 10, 2025	N433309
F2505449	Certificate of Analysis	Apr 10, 2025	N433309
F2505475	Certificate of Analysis	Apr 10, 2025	N433309
K2413146	Certificate of Analysis	Sep 04, 2024	N433309
I2419643	Certificate of Analysis	Sep 04, 2024	N433309
I2419645	Certificate of Analysis	Sep 04, 2024	N433309
D2424339	Certificate of Analysis	Apr 11, 2024	N433309
D2424340	Certificate of Analysis	Apr 11, 2024	N433309
D2424341	Certificate of Analysis	Apr 11, 2024	N433309
K2313538	Certificate of Analysis	Oct 27, 2023	N433309
K2313485	Certificate of Analysis	Oct 27, 2023	N433309
I2301568	Certificate of Analysis	Aug 18, 2023	N433309
I2301567	Certificate of Analysis	Aug 18, 2023	N433309
A2411664	Certificate of Analysis	Mar 24, 2023	N433309
A2411665	Certificate of Analysis	Mar 24, 2023	N433309

Proprietà chimiche e fisiche

Indice di rifrazione	1.4269
Punto di infiammabilità (°F)	136.4 °F
Punto di infiammabilità (°C)	58℃
Punto di ebollizione (°C)	152.8°C
Punto di fusione (°C)	-61°C
Peso molecolare	73.090 g/mol
XLogP3	-1.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	73.0528 Da
Monoisotopic Mass	73.0528 Da
Topological Polar Surface Area	20.300 Å²
Heavy Atom Count	5
Formal Charge	0
Complexity	33.900
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Specification Purity Grade UltraPureChrom for HPLC Suitable for HPLC

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One-Stop Handbook for Palladium-Catalyzed Reactions: Catalytic Cycles, Deactivation Troubleshooting, Ligand/Precatalyst Selection, and an Aladdin Reference List

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Pd Palladium-Catalyzed Reactions

A Complete Guide to Choosing Resins for SPPS (Solid-Phase Peptide Synthesis): Fmoc/Boc Routes, C-Terminal Acid/Amide, and a Key-Parameter Navigator

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SPPS Solid-Phase Peptide Synthesis

Installing a Redox Switch on Biomolecules: Principles, Conjugation Essentials, and an Application Guide for ATTO MB2 NHS ester

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ATTO MB2 NHS ester Redox Switch

A Practical Guide to Small-Molecule Chemical Probes: Concept Clarification, Causal Validation, and Experimental Selection (with Product Navigation and Tables A–D)

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Chemical probe Small-Molecule Chemical Probes

Practical Guide to Carbon Nanotube (CNT) Dispersion: Three Key Knobs, SOP, and Selection Roadmap (Tables A–F)

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Carbon Nanotube

From Piperidine to Pyridine: The “Most Common N-Heterocycle” Shift in FDA Small-Molecule New Drugs (2013–2023) and a Selection Guide (Tables 1–4)

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Structural–Functional Analysis of the Methoxy Group (–OCH₃) in Approved Small-Molecule Drugs: Mechanisms, Evidence Chains, and Product-Selection Navigation (with Related Product Tables)

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A Practical Guide to Organozinc Reagents for Synthesis (Organozinc Reagents): Structural Features, Key Reactions, and a Practical Selection Navigation (Including Aladdin Product Tables)

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Organozinc reagents

Why Acridine Can Turn “Trace Molecules” into a Measurable Light Signal: A Mechanistic, Selection, and Troubleshooting Guide to Acridinium Ester Chemiluminescent Immunoassays (Including Product Tables 1–4)

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β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention

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From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC

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New Progress in the Solid-Phase Synthesis of Sterically Hindered Peptides: Background, Core Breakthroughs, and Implications for Automation Compatibility of the RMMR Strategy

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Reassessing Trimethylaluminum: Method Design and Experimental Value of One-Pot Peptide Elongation from Unprotected Amino Acids

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What a Disagreement in Specific Rotation Results Reveals About Method Control: Why Specific Rotation Values for Chiral Samples Cannot Be Discussed Apart from Measurement Conditions

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Phthaloyl: Its Role in Primary Amine Protection and Practical Considerations for Experimental Selection

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Phthaloyl Phth

The Methodological Value of HATU in Difficult Couplings: Reactivity Advantages, Stereochemical Retention, and Condition Management

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HATU

Low Racemization in Peptide Synthesis Is Not Just About Reagent Choice: Stereochemical Risk During the Activation Stage and Practical Strategies for Experimental Control

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DSC N,N′-disuccinimidyl carbonate

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carboxylic acid TCFH coupling reagents Strong condensing reagent

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carbamate Boc₂O Boc protection

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Coupling Oxyma Coupling Systems Oxyma ethyl 2-cyano-2-(hydroxyimino)acetate OxymaPure

Polyetherimide (PEI): Structural Features, Main Properties, and Typical Application Directions

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PEI Polyetherimide

From Functional Groups to Experimental Decision-Making: Protein Crosslinker Selection and Experimental Essentials

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Functional Groups Crosslinkers

Metal Halide Perovskite Solar Cells: Sources of High Efficiency, Stability Bottlenecks, and Experimental Decision Logic

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perovskite Solar cell Metal halides

How to Troubleshoot Abnormal Impurities in Peptide Synthesis? Locating Process Issues Through Amino-Related Side Reactions

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Peptide synthesis Abnormal impurities

Peptide Intermediates Difficult to Dissolve and Separate? Route Design and Workup Strategies for Tag-Assisted Liquid-Phase Peptide Synthesis (TAG-LPPS)

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Peptide synthesis TAG-LPP Peptide Intermediates

AITF-Mediated Carboxylic Acid Activation for the Synthesis of Amides, Peptides, and Esters: Activation Mechanism and Applicable Scenarios

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Peptides AITF Amides Esters

Formation and Control of Carboxyl- and Hydroxyl-Related Impurities in Peptide Synthesis — Using Asp/Glu and Ser/Thr Residue Side Reactions as Examples

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Peptide synthesis Functional Group Carboxyl group

Selenium

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Chemical synthesis Reducing agent Active Reduction

CTSOBt Benzotriazole–Sulfonate Coupling Reagent: Carboxylic Acid Activation and Synthetic Application Value

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Peptide synthesis coupling reagent coupling reagents

From Photocatalytic Ring Opening to Skeletal Reconstruction: Reaction Logic and Synthetic Applications of Oxygen-Atom Replacement in Oxetanes

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Photocatalysts Saturated quaternary ring Skeleton

Logic for Selecting Amidation Reagents in Aqueous Media: Competing Reactions, Activated Intermediates, and Substrate Effects

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Amidation reaction

Sulfonyl Hydrazide-Mediated Introduction of Small C(sp³) Fragments: Nickel-Catalyzed Cross-Coupling, Medicinal Chemistry Applications, and Reagent Selection

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From Nucleophilic to Electrophilic BCB Synthetic Equivalents: Hypervalent-Iodine-Mediated Umpolung Design

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BCB bicyclo[1.1.0]butane

From Functional-Group Transformation to Intramolecular Cyclization: Reaction-Pathway Analysis of TMSCl/DMF-Promoted Annulation and CuCN-Mediated Cascade Cyclization

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Organic synthesis trimethylsilyl chloride TMSCl N,N-dimethylformamide DMF

Medicinal Chemistry Design of the Indazole Scaffold: Tautomerism, Molecular Recognition, Substitution-Site Design, and Synthetic Strategies

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Indazole Nitrogen-containing aromatic heterocycles

Discovery and Structural Optimization of the Noncovalent 3CL Protease Inhibitor S-217622

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3C-like protease main protease

How Cyclization Changes Peptide Behavior: Conformational Preorganization, Skin Delivery, and Integrin Binding, Using Cyclopeptide-5 as an Example

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Polypeptide Skincare

How to Bypass α-Fluoride Elimination: Bromine-Transfer Capture and Oxidative Coupling of α,α-Difluorobenzylic Anions

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Deprotonation

Reactions and Applications of 3,3-Difluoroallyl Sulfonium Salts (DFASs): Small-Molecule gem-Difluoroallylation, Selective Peptide Modification, and Subsequent Functionalization

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Polypeptide Fluorinated groups

Why Primary and Secondary Amines Have Difficulty Participating Directly in the Classical Mitsunobu Reaction: Mechanism, Inversion of Configuration, and Reaction Scope of BEHT-Mediated Alcohol Amination

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Mitsunobu Reaction BEHT Protonated Betaine Alcohol Activation Primary Amines Secondary Amines Bimolecular Nucleophilic Substitution Inversion Of Configuration Α-Chiral Amines

Mechanistic Basis of Acetyl Hexapeptide-8 in the Management of Expression Lines: SNARE Complex Interference, Constraints on Percutaneous Delivery, and Combination Strategies

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Retinol Acetyl Hexapeptide-8 Argireline SNAP-25 SNARE complex expression lines transdermal delivery anti-wrinkle combinations

Copper Tripeptide GHK-Cu and Skin Repair: From Copper Coordination Chemistry to Extracellular Matrix Remodeling

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Extracellular matrix Skin Repair ECM GHK-Cu

Direct Construction of Methylsulfonyl-Containing Heterocycles: Synthesis and Applications of Prefunctionalized Three-Carbon Vinamidinium Salts

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–SO₂CH₃ –SO₂Me

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Tether Effects in Intramolecular [2+2] Photocycloadditions: Straight and Crossed Regioselectivity and Stepwise C–C Bond Formation

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Screening and Replacement of Green Solvents in Metallaphotoredox Catalysis: Reaction Compatibility and Process Feasibility

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Photocatalytic

ACT-1014-6470 Kilogram-Scale Synthesis: N7-Selective Reductive Amination of an Unprotected Pyrazole, Subsequent N2 Alkylation, and Intramolecular Urea Formation

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reductive amination Pyrazole

Bond-Formation Sequence and Process Improvement for 3-Bromo-6-alkyl-1,6-naphthyridin-5(6H)-ones: From Late-Stage N-Alkylation to Enamine Cyclization with Primary Amines

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Enamine cyclization 3-bromo-N-alkyl-1,6-naphthyridones

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N,N-Dimethylformamide (DMF) - UltraPureChrom™, for GC-HS , CAS No.68-12-2

Storage & shipping

Quality documents

Literature proof

Panoramica

Specifications

Documentazione

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Recensioni dei clienti

📚 Citations by Application

Need help choosing the grade?

View related series

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