Amiloride - Moligand™, 10 mM in DMSO , CAS No.2609-46-3

CAS: 2609-46-3 Cat. No.: A1499343 Fórmula: C₆H₈ClN₇O Peso molecular: 229.63 Beilstein Registry Number: 616612 Número CE: 220-024-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Amiloride (MK-870) is an inhibitor of both epithelial sodium channel ( ENaC) and urokinase-type plasminogen activator receptor ( uTPA). Amiloride is a blocker of polycystin-2 (PC2; TRPP2) channel.

Specifications

Especificações e pureza

Moligand™, 10 mM in DMSO

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Propriedades do produto

• pKa: pKa: 7.81 (Predicted), pKa: 3.78 (Predicted)
• Dados Ki: uPA: Ki= 2.51 μM (human); Adenosine A2A-R: Ki= 3.28 μM (human); Solute carrier family 22 member 2: Ki= 4.7 μM (rat); Solute carrier family 22 member 1: Ki= 6.9 μM (rat); Amine oxidase, copper containing: Ki= 10 μM (rat)

Nomes e identificadores

• SMILES isoméricas: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
• CAS alternativo: 2016-88-8;17440-83-4
• Peso molecular: 229.63
• Beilstein: 616612

Propriedades químicas e físicas

• Índice de refração: n20D1.89 (Predicted)
• Ponto de ebulição (°C): ~557.9° C at 760 mmHg (Predicted)
• Ponto de fusão (°C): 185.21° C (Predicted)

Referências

1. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:35487070] [10.1016/j.colsurfb.2022.112505]

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2609-46-3, the molecular formula is C6H8ClN7O, and the molecular weight is 229.63 g/mol.