CGP 44532 - Moligand™ , Agonist of GABA B receptor, CAS No.133345-68-3, Agonist of GABA B receptor

CAS: 133345-68-3 Cat. No.: C608502 PubChem CID: 5310934

GRAU & PUREZA Moligand™

Synonyms

CGP44533|CGP-44533|(3-Amino-2(R)-hydroxypropyl)methylphosphinic acid|Phosphinic acid, P-((2R)-3-amino-2-hydroxypropyl)-P-methyl-|P-[3-amino-2(R)-hydroxy-propyl]-P-methyl-phosphinic acid|((2R)-3-Amino-2-hydroxypropyl)-methylphosphinic acid|[(2R)-3-amino-2-hydroxypropyl]-methylphosphinic acid|Phosphinic acid, P-[(2R)-3-amino-2-hydroxypropyl]-P-methyl-|CGP 44533|CGP 44532|starbld0007694|((R)-3-Amino-2-hydroxypropyl)(methyl)phosphinic acid|P-((2R)-3-Amino-2-hydroxypropyl)-P-methylphosphinic acid|Phosphinic acid, (3-amino-2-hydroxypropyl)methyl-, (R)-|P-[(2R)-3-Amino-2-hydroxypropyl]-P-methylphosphinic acid

Storage

Room temperature

Especificações

Sinónimos

CGP44533 | CGP-44533 | (3-Amino-2(R)-hydroxypropyl)methylphosphinic acid | Phosphinic acid, P-((2R)-3-amino-2-hydroxypropyl)-P-methyl- | P-[3-amino-2(R)-hydroxy-propyl]-P-methyl-phosphinic acid | ((2R)-3-Amino-2-hydroxypropyl)-methylphosphinic acid | [(2R)-3-amino-2-hydroxypropyl]-methylphosphinic acid | Phosphinic acid, P-[(2R)-3-amino-2 Show more

Especificações e pureza

Moligand™

Condições de armazenamento de armazenamento

Room temperature

Grau

Moligand™

Tipo de ação

AGONIST

Mecanismo de ação

Agonist of GABA B receptor

Nomes e identificadores

Sorrisos canónicos

CP(=O)(C[C@@H](CN)O)O

IUPAC Name

[(2R)-3-amino-2-hydroxypropyl]-methylphosphinic acid

InChIKey

FUUPFUIGNBPCAY-SCSAIBSYSA-N

INCHI

1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h4,6H,2-3,5H2,1H3,(H,7,8)/t4-/m1/s1

SMILES isoméricas

CP(=O)(C[C@@H](CN)O)O

PubChem CID

5310934

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Amines
        • Level5 Alkanolamines
          • Level6 1,2-aminoalcohols

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Alkanolamines
• Direct Parent: 1,2-aminoalcohols
• Alternative Parents: Secondary alcohols Organophosphorus compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Secondary alcohol - 1,2-aminoalcohol - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organophosphorus compound - Organooxygen compound - Primary aliphatic amine - Alcohol - Aliphatic acyclic compound
• Descrição: This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

GABRR1 Tchem Gamma-aminobutyric acid receptor subunit rho-1 (1 Activities)

Discover Target: GABRR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCTD8 Tbio BTB/POZ domain-containing protein KCTD8 (0 Activities)

Discover Target: KCTD8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABBR2 Tclin Gamma-aminobutyric acid type B receptor subunit 2 (0 Activities)

Discover Target: GABBR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABBR1 Tclin Gamma-aminobutyric acid type B receptor subunit 1 (0 Activities)

Discover Target: GABBR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCTD12 Tchem BTB/POZ domain-containing protein KCTD12 (0 Activities)

Discover Target: KCTD12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCTD16 Tbio BTB/POZ domain-containing protein KCTD16 (0 Activities)

Discover Target: KCTD16

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GABRR1 Tchem GABA receptor rho-1 subunit (233 Activities)

Discover Target: GABRR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Alvos associados (não humanos)

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 153.120 g/mol
• XLogP3: -4.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 153.055 Da
• Monoisotopic Mass: 153.055 Da
• Topological Polar Surface Area: 83.600 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 127.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 133345-68-3. InChIKey FUUPFUIGNBPCAY-SCSAIBSYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.