CTDSP1 Antibody - Primary antibody, specific to CTDSP1, Rabbit IgG

Cat. No.: Ab098042

GRADE & PURITY Carrier Free, ExactAb™, Validated, 1.0 mg/mL

Application

IHC, WB

Host species

Rabbit

Reactive species

Human, Mouse, Rat

Isotype

Rabbit IgG

Conjugation

Unconjugated

Visão geral

Rabbit anti Human CTDSP1 Antibody, Polyclonal, could be used for WB, IHC and so on.

Application

WB: 1/500-1/1000

IHC: 1/50-1/100

Protein Function

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Specifications

Product Name

CTDSP1 Antibody - Primary antibody, specific to CTDSP1, Rabbit IgG

Sinónimos

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody | Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody | CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1

Especificações e pureza

ExactAb™, Validated, Carrier Free, 1.0 mg/mL

Espécie hospedeira

Rabbit

Especificidade

CTDSP1

Imunogénio

A KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CTDSP1.

Controlo positivo

WB: Mouse skeletal muscle, Mouse spleen, Rat spleen, A549, HeLa, HEL and NIH/3T3 lysates. IHC: Human breast cancer tissue.

Conjugação

Unconjugated

Grau

Carrier Free, ExactAb™, Validated

Isótipo

Rabbit IgG

SDS-PAGE

150 kDa

Método de purificação

Immunogen affinity purified

Concentração

1.0 mg/mL

Product Line

biological_products

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Western Blot: CTDSP1 Antibody (Ab098042)

CTDSP1 Antibody (Ab098042) - Western Blot
All lanes: CTDSP1 Antibody (Ab098042) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/10000 dilution
Predicted band size: 29 kDa
Observed band size: 28 kDa
Exposure time: 33.0 s

IHC: CTDSP1 Antibody (Ab098042)

CTDSP1 Antibody (Ab098042) - IHC
Immunohistochemical analysis of CTDSP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with CTDSP1 Antibody (Ab098042) at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Aplicação

Aplicação

Dilution info

WB

1/500-1/1000

IHC

1/50-1/100

Alvos associados (humanos)

CTDSP1 Tchem Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (0 Activities)

Discover Target: CTDSP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (CTDSP1 Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.